Results 1 to 10 of about 8,706 (198)

Neutrophil extracellular traps and phagocytosis in Pythium insidiosum. [PDF]

PLoS One, 2023
Neutrophils are innate immune cells that play crucial roles in response to extracellular pathogens, including bacteria and fungi. Pythium insidiosum (P insidiosum) is a fungus-like pathogen that causes "pythiosis" in mammals. This study investigated in vitro function of human neutrophils against P. insidiosum.
Sriwarom A, Chiewchengchol D, Saithong S, Worasilchai N, Chindamporn A.   +4 more
europepmc   +7 more sources

Pythium insidiosum keratitis - A review [PDF]

Indian Journal of Ophthalmology, 2022
Pythium insidiosum is an oomycete and is also called “parafungus” as it closely mimics fungal keratitis. The last decade saw an unprecedented surge in Pythium keratitis cases, especially from Asia and India, probably due to growing research on the ...
BharatGurnani, KirandeepKaur, AnithaVenugopal, BhaskarSrinivasan, BhupeshBagga, GeethaIyer, JosephineChristy, LalithaPrajna, MurugesanVanathi, PrashantGarg, ShivanandNarayana, ShwetaAgarwal, SrikantSahu   +12 more
doaj   +4 more sources

Comparative Genomic Analysis Reveals Gene Content Diversity, Phylogenomic Contour, Putative Virulence Determinants, and Potential Diagnostic Markers within Pythium insidiosum Traits [PDF]

Journal of Fungi, 2023
Pythium insidiosum has successfully evolved into a human/animal filamentous pathogen, causing pythiosis, a life-threatening disease, worldwide. The specific rDNA-based genotype of P. insidiosum (clade I, II, or III) is associated with the different hosts
Weerayuth Kittichotirat, Thidarat Rujirawat, Preecha Patumcharoenpol, Theerapong Krajaejun   +3 more
doaj   +3 more sources

Potential anti- Pythium insidiosum therapeutics identified through screening of agricultural fungicides [PDF]

Microbiology Spectrum
Pythiosis is a life-threatening infectious disease caused by the oomycete Pythium insidiosum. Clinical manifestations of pythiosis include an eye, blood vessel, skin, or gastrointestinal tract infection. Pythiosis has been increasingly reported worldwide,
Weerayuth Kittichotirat, Duangdao Wichadakul, Theerapong Krajaejun   +2 more
exaly   +4 more sources

Severe skin and subcutaneous pythiosis in China: Metagenomic identification and characterization of Pythium insidiosum [PDF]

Frontiers in Microbiology, 2022
Pythium insidiosum is a rare fungus-like pathogen that is known to cause pythiosis in mammals with high morbidity and mortality. Identification of the pathogen is essential for timely treatment and rational use of antibiotics. However, Pythium insidiosum
Haiyan Zhang, Fengli Zhou, Jiabao Huang, Xiaoyun Liu, Hui Xu, Jiayin Liang, Jun Wang, Jing Chen, Lingling Liu, Yiting Li, Xuan Hu, Xuanrong Chen, Chao Liu, Kouxing Zhang, Kouxing Zhang   +14 more
doaj   +2 more sources

Iron overload is associated with increased susceptibility to pulmonary Pythium insidiosum infection in mice. [PDF]

PLoS Neglected Tropical Diseases
BackgroundPythium insidiosum is a fungus-like oomycete capable of causing disease with high mortality rates. Although pulmonary Pythium insidiosum infections are rare, they are associated with an extremely high fatality rate.
Donglin Zhu, Ling Yan, Jian Sun, Shaoban Chen, Yun Xi, Kouxing Zhang, Mingliang Li   +6 more
doaj   +2 more sources

Role of Immunotherapy in Pythium insidiosum Keratitis. [PDF]

Am J Trop Med Hyg, 2022
ABSTRACT. Pythium keratitis is a potentially devastating ocular condition. Incidence of Pythium keratitis has been reported in tropical and subtropical areas. In previous reports, there were no effective or standard treatments, and combinations of medication, immunotherapy, and surgery were proposed.
Thanathanee O, Bhoomibunchoo C, Anutarapongpan O, Suwan-Apichon O, Charoensuk K, Chindamporn A.   +5 more
europepmc   +3 more sources

Pythium insidiosum Keratitis: Past, Present, and Future. [PDF]

Ophthalmol Ther, 2022
Pythium insidiosum (PI) is an oomycete, a protist belonging to the clade Stramenopila. PI causes vision-threatening keratitis closely mimicking fungal keratitis (FK), hence it is also labeled as "parafungus". PI keratitis was initially confined to Thailand, USA, China, and Australia, but with growing clinical awareness and improvement in diagnostic ...
Gurnani B, Kaur K, Agarwal S, Lalgudi VG, Shekhawat NS, Venugopal A, Tripathy K, Srinivasan B, Iyer G, Gubert J.   +9 more
europepmc   +4 more sources

MGI short-read genome assemblies of Pythium insidiosum (reclassified as Pythium periculosum) strains Pi057C3 and Pi050C3 [PDF]

BMC Research Notes, 2023
Objectives Pythium insidiosum causes a difficult-to-treat infectious condition called pythiosis, with high morbidity and mortality. So far, genome data of at least 10 strains of P.
Theerapong Krajaejun, Preecha Patumcharoenpol, Thidarat Rujirawat, Weerayuth Kittichotirat, Sithichoke Tangphatsornruang   +4 more
doaj   +2 more sources

PacBio long read-assembled draft genome of Pythium insidiosum strain Pi-S isolated from a Thai patient with pythiosis [PDF]

BMC Research Notes, 2023
Objectives Pythium insidiosum is the causative agent of pythiosis, a difficult-to-treat condition, in humans and animals worldwide. Biological information about this filamentous microorganism is sparse. Genomes of several P.
Theerapong Krajaejun, Preecha Patumcharoenpol, Thidarat Rujirawat, Weerayuth Kittichotirat, Sithichoke Tangphatsornruang, Tassanee Lohnoo, Wanta Yingyong   +6 more
doaj   +2 more sources