Results 71 to 80 of about 30,071 (267)

RHINO: An Integrative Multi‐Omics Framework Linking Circadian Physiology to Precision Medicine

open access: yesAdvanced Science, EarlyView.
RHINO (RHythmic Interacting Network for multi‐Omics) is an integrative framework that maps circadian regulation across diverse genetic and disease contexts and prioritizes druggable circadian targets. Released as an AI‐powered interactive web portal, RHINO unifies genetic, regulatory, disease, and drug–target information, enabling context‐specific ...
Ying Chen   +12 more
wiley   +1 more source

Python Introduction and Installation

open access: yesThe Programming Historian, 2012
This first lesson in our section on dealing with Online Sources is designed to get you and your computer set up to start programming. We will focus on installing the relevant software – all free and reputable – and finally we will help you to get your ...
William J. Turkel, Adam Crymble
doaj  

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

open access: yesAdvanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

The Two Powers: How Pascal and Python Shaped Programming Education

open access: yesInformatics in Education
The choice of programming language for education is an intensely debated topic. On the one hand, the programming language is supposed to be relevant in that its organisation, structures, and paradigms adhere to current standards and best practices in ...
Tobias Kohn, Jacqueline Staub
doaj   +1 more source

PCSIM: a parallel simulation environment for neural circuits fully integrated with Python

open access: yesFrontiers in Neuroinformatics, 2009
The Parallel Circuit SIMulator (PCSIM) is a software package for simulation of neural circuits. It is primarily designed for distributed simulation of large scale networks of spiking point neurons. Although its computational core is written in C++, PCSIM'
Dejan Pecevski   +2 more
doaj   +1 more source

Stochastic Entanglement of Deterministic Origami Tentacles For Robust Robotic Grasping

open access: yesAdvanced Science, EarlyView.
This study introduces an origami tentacle gripper to robustly grasp objects‐in air, underwater, and even in orbital space‐by exploiting a synergy between local, deterministic deformation programming and global, stochastic entanglements. A single origami tentacle can be designed to coil with a simple tendon pull.
Alec Boron   +4 more
wiley   +1 more source

Usage of the Python programming language in the CMS experiment

open access: yesJournal of Physics: Conference Series, 2010
Being a highly dynamic language and allowing reliable programming with quick turnarounds, Python is a widely used programming language in CMS. Most of the tools used in workflow management and the GRID interface tools are written in this language. Also most of the tools used in the context of release management: integration builds, release building and
R Wilkinson, B Hegner, C D Jones
openaire   +1 more source

Receptogenesis in a Vascularized Robotic Embodiment

open access: yesAdvanced Science, EarlyView.
Functional augmentation of situated robots via ex novo hardware generation extends physical adaptability. Drawing inspiration from open circulatory systems for mass and function redistribution, this study presents a vascularized robotic composite exhibiting receptogenesis ‐ the on‐demand construction of sensors ‐ from internal fluid reserves based on ...
Kadri‐Ann Pankratov   +8 more
wiley   +1 more source

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