Results 41 to 50 of about 2,041,568 (299)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Forensic Construction-Family Signatures in Solved RSA Challenge Moduli: High-Bit Conditioning, Residue Constraints, and Factor-Balance Patterns

Information
RSA moduli may retain arithmetic evidence of prime-selection constraints. We analyse 22 solved formal RSA Challenge moduli (44 factors), excluding RSA-129 and treating 18 original decimal-labelled entries separately from four later bit-labelled entries ...
Anthony Overmars, Sitalakshmi Venkatraman   +1 more
doaj   +1 more source

Improve Quality Factor by Using DWDM Technology for Long Distances and Different Power Levels

Journal of Techniques, 2022
In optical fiber communications, data travels from the transmitter to the receiver, where it is collected and converted from optical pulses into electrical signals. The need for bandwidth has grown significantly in recent years.
Mariam lazem, Ali Mahdi Hammadi, Ali Al-Askery   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Luby Transform Coding Aided Bit-Interleaved Coded Modulation for the Wireless Internet [PDF]

, 2007
Bit-Interleaved Coded Modulation using Iterative Decoding (BICM-ID) is amalgamated with Luby Transform (LT) coding. The resultant joint design of the physical and data link layer substantially improves the attainable Bit Error Rate (BER) performance.
Nguyen Dang, T, Ng, S, Tee, R, Yang, L-L, Hanzo, L   +4 more
core   +2 more sources

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

BER Performance Analysis of Non-Coherent Q-Ary Pulse Position Modulation Receivers on AWGN Channel

Sensors, 2021
This paper introduces the structure of a Q-ary pulse position modulation (PPM) signal and presents a noncoherent suboptimal receiver and a noncoherent optimal receiver.
Xianhua Shi, Yimao Sun, Jie Tian, Maolin Chen, Youjiang Liu, Nan Xie, Jian Zhang   +6 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Efficient pattern matching in compressed text via bit-parallel word-based encoding

Franklin Open
This paper introduces an optimized algorithm designed to accelerate compressed word matching using advanced bit-parallelism techniques, resulting in a high-performance solution. The proposed algorithm (BIT_COMP) uses the concept of word-based tagged code
Rajesh Prasad, Santosh Kumar Upadhyay, Vikas, Surya Prakash Mishra   +3 more
doaj   +1 more source

Joint high-dimensional soft bit estimation and quantization using deep learning

EURASIP Journal on Wireless Communications and Networking, 2022
Forward error correction using soft probability estimates is a central component in modern digital communication receivers and impacts end-to-end system performance.
Marius Arvinte, Sriram Vishwanath, Ahmed H. Tewfik, Jonathan I. Tamir   +3 more
doaj   +1 more source