Results 81 to 90 of about 2,972,572 (324)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A note on (p,q) $(p,q)$-Bernstein polynomials and their applications based on (p,q) $(p,q)$-calculus

open access: yesJournal of Inequalities and Applications, 2018
Nowadays (p,q) $(p,q)$-Bernstein polynomials have been studied in many different fields such as operator theory, CAGD, and number theory. In order to obtain the fundamental properties and results of Bernstein polynomials by using (p,q) $(p,q)$-calculus ...
Erkan Agyuz, Mehmet Acikgoz
doaj   +1 more source

Deformed Heisenberg algebra: origin of q-calculus [PDF]

open access: yesPhysica A: Statistical Mechanics and its Applications, 2003
11 ...
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Was the Early Calculus an Inconsistent Theory? [PDF]

open access: yes, 2007
The ubiquitous assertion that the early calculus of Newton and Leibniz was an inconsistent theory is examined. Two different objects of a possible inconsistency claim are distinguished: (i) the calculus as an algorithm; (ii) proposed explanations of the ...
Vickers, Peter
core  

A Calculus of Mobile Resources

open access: yes, 2002
We introduce a calculus of Mobile Resources (MR) tailored for the design and analysis of systems containing mobile, possibly nested, computing devices that may have resource and access constraints, and which are not copyable nor modifiable per se.
Godskesen, J.Chr.   +8 more
core   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Pseudo-Quantum Fractional Calculus and Existence of Solutions for Delay Pseudo-Fractional Differential Equations in Generalized Banach Spaces

open access: yesJournal of Mathematics
This paper presents a new framework of pseudo-q–fractional calculus in generalized Banach spaces by bringing together pseudo-analysis, G–calculus, and quantum calculus. We introduce Liouville–Caputo and Riemann–Liouville pseudo-q–fractional operators and
Alireza Hatami   +3 more
doaj   +1 more source

Exploring Fractional $q$-Kinetic Equations via Generalized $q$-Mittag-Leffler Type Functions: Applications and Analysis [PDF]

open access: yesSahand Communications in Mathematical Analysis
In this study, the $q$-calculus is employed to introduce a novel generalization of the Mittag-Leffler function. In the following, we investigate a novel $q$-exponential function with five parameters, resulting in the generalized $q$-Mittag-Leffler ...
Mulugeta Dawud Ali   +2 more
doaj   +1 more source

Fisher information, Borges operators, and q-calculus

open access: yesPhysica A: Statistical Mechanics and its Applications, 2008
Abstract We discuss applying the increasingly popular q -calculus, or deformed calculus, so as to suitably generalize Fisher’s information measure and the Cramer–Rao inequality. A q -deformation can be attained in multiple ways, and we show that most of them do not constitute legitimate procedures. Within such a context, the only completely
Pennini, F., Plastino, A., Ferri, G. L.
openaire   +3 more sources

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