Results 111 to 120 of about 2,203,972 (289)

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Quasi-subordination for a subclass of non-Bazilevic functions connected with a q-derivative operator [PDF]

This study examines a broad subclass of non-Bazileviˇc functions that includes several subclasses of q-bounded turning functions and q-Sakaguchi functions.
Ayotunde Olajide Lasode, Risikat Ayodeji Bello, Rasheed Olawale Ayinla, Adediran Dauda Adeshola   +3 more
core   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Efficient Scheme for Solving Tempered Fractional Quantum Differential Problem

Fractal and Fractional
This study presents a novel family of operators, referred to as tempered quantum fractional operators, and investigates the well-posedness of related tempered quantum fractional differential equations.
Lakhlifa Sadek, Ali Algefary
doaj   +1 more source

Dynamics and applications of quantum iterative methods [PDF]

Iranian Journal of Numerical Analysis and Optimization
In this article, we have introduced a new type of parametric family of the Quantum iterative method (PFQIM) using quantum derivative ($q$-derivative) to solve non-linear equations.
Sapan Nayak, P. Parida, Babita Mehta
doaj   +1 more source

Fekete-Szego problem for certain analytic functions defined by q−derivative operator with respect to symmetric and conjugate points

, 2018
Recently, the q−derivative operator has been used to investigate several subclasses of analytic functions in different ways with different perspectives by many researchers and their interesting results are too voluminous to discuss.
Olatunji, S. O., Dutta, H.
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Certain subclass of alpha-convex bi-univalent functions defined using $q$-derivative operator [PDF]

summary:The present investigation deals with a new subclass of alpha-convex bi-univalent functions in the unit disc $E=\left\rbrace z\colon \mid z \mid
Singh, Gurcharanjit, Singh, Gagandeep
core   +1 more source