Results 131 to 140 of about 2,570,036 (296)

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

A Study of an Extended q-Mittag−Leffler Function and Its Image Formula Under the Kober Fractional q-Calculus Operator

International Journal of Mathematics and Mathematical Sciences
This study uses the q-calculus to present an innovative extension of the q-Mittag−Leffler function. Next, we examine some of its notable characteristics, including image formula under the Kober fractional q-calculus operator, recurrence relation and ...
Mulugeta Dawud Ali, D. L. Suthar
doaj   +1 more source

Differentiating under $q$-integral sign

Hacettepe Journal of Mathematics and Statistics
The Leibniz integral rule enables us to interchange the order of differentiation and integration under some differentiability conditions on the functions. It can be very useful in the computing the exact value of certain integrals. In this paper, we will present analogs of such rule for $q$-integrals with functional borders and their properties.
Predrag Rajković, Sladjana D. Marinkovic   +1 more
openaire   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

A Note on Extended Saigo Operators and Their q-analogues

Известия Иркутского государственного университета: Серия "Математика"
Megumi Saigo derived generalized fractional operators, involving Gauss hypergeometric function, having four special cases: Riemann-Liouville, Weyl, Erd´elyKober left and right sided fractional operators.
K. K. Chaudhary, S. B. Rao
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Proof of 5D A n AGT conjecture at β = 1

Journal of High Energy Physics
In this paper, we give a proof of 5D A n AGT conjecture at β = 1, where the gauge theory side is one dimension higher than the original 4D case, and corresponds to the q-deformation of the 2D conformal field theory side.
Qian Shen, Zi-Hao Huang, Shao-Ping Hu, Qing-Jie Yuan, Kilar Zhang   +4 more
doaj   +1 more source

A First Order q-Difference System for the BC_1-Type Jackson Integral and Its Applications

Symmetry, Integrability and Geometry: Methods and Applications, 2009
We present an explicit expression for the q-difference system, which the BC_1-type Jackson integral (q-series) satisfies, as first order simultaneous q-difference equations with a concrete basis.
Masahiko Ito
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source