Results 41 to 50 of about 3,688,282 (260)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
On matrix models and their q-deformations
Journal of High Energy Physics, 2020 Motivated by the BPS/CFT correspondence, we explore the similarities be- tween the classical β-deformed Hermitean matrix model and the q-deformed matrix models associated to 3d N $$ \mathcal{N} $$ = 2 supersymmetric gauge theories on D 2 × q S 1 and S b ...
Luca Cassia +2 more
doaj +1 more source
Some upper bounds for the signless Laplacian spectral radius of digraphs [PDF]
Transactions on Combinatorics, 2019 Let $G=(V(G),E(G))$ be a digraph without loops and multiarcs, where $V(G)=\{v_1,v_2,$ $\ldots,v_n\}$ and $E(G)$ are the vertex set and the arc set of $G$, respectively. Let $d_i^{+}$ be the outdegree of the vertex $v_i$.
Weige Xi, Ligong Wang
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Mappings Ideal of Type the Domain of Generalized p,q-Euler Matrix in c0 and c
Journal of Mathematics, 2023 We develop new Banach sequence spaces e0a,bp,q and eca,bp,q derived by the domain of generalized p,q-Euler matrix Ea,bp,q in the spaces of null and convergent sequences, respectively.
Taja Yaying +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Superintegrability for some (q, t)-deformed matrix models
European Physical Journal C: Particles and FieldsWe analyze the Macdonald’s (q, t)-deformed hypergeometric functions with one and two set variables and present their constraints. We prove the uniqueness to the solutions of these constraints.
Fan Liu +3 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Visual servoing with deep reinforcement learning for rotor unmanned helicopter
International Journal of Advanced Robotic Systems, 2022 Visual servoing is a key approach to achieve visual control for the rotor unmanned helicopter. The challenges of the inaccurate matrix estimation and the target loss restrict the performance of the visual servoing control systems.
Chunyang Hu, Wenping Cao, Bin Ning
doaj +1 more source