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A New Generalization of Legendre-Based Appell Polynomials with Two Parameters and Their Applications

Axioms
In the present work, we introduce and study a new two-parameter generalization of Legendre-based Appell polynomials, defined through an explicit representation that unifies classical Legendre structures with the Appell polynomial framework. Starting from
Ghaliah Alhamzi, Georgia Irina Oros, Mdi Begum Jeelani, Kalika Prasad, Shahid Ahmad Wani   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

AdS vacua of non-supersymmetric strings

Journal of High Energy Physics
Few vacua are known for the three tachyon-free non-supersymmetric string theories. We find new classes of AdS backgrounds by focusing on spaces where the equations of motion reduce to purely algebraic conditions. Our first examples involve non-zero three-
Salvatore Raucci, Alessandro Tomasiello
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Random Fibonacci Words via Clone Schur Functions

Forum of Mathematics, Sigma
We investigate positivity and probabilistic properties arising from the Young–Fibonacci lattice $\mathbb {YF}$ , a 1-differential poset on words composed of 1’s and 2’s (Fibonacci words) and graded by the sum of the digits.
Leonid Petrov, Jeanne Scott
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

q-identities from Lagrange and Newton interpolation [PDF]

, 2003
Combining Newton and Lagrange interpolation, we give q-identities which generalize results of Van Hamme, Uchimura, Dilcher, and ...
Lascoux, Alain, Amy M. Fu, Alain Lascoux, Fu, Amy M.   +3 more
core   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

$q$-Binomial Identities Finder [PDF]

This paper presents a symbolic computation method for automatically transforming $q$-hypergeometric identities to $q$-binomial identities. Through this method, many previously proven $q$-binomial identities, including $q$-Saalsch\"utz's formula and $q ...
Zhao, Leqi, Zhong, Hao
core  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source