Results 61 to 70 of about 80,318 (305)

Ytterbium- and chromium-doped fibre laser: from chaotic self-pulsing to passive Q-switching [PDF]

, 2011
A spontaneously chaotic, self-pulsing ytterbium-doped fibre laser is partially stabilized into the passively Q-switched mode of operation using a chromium-doped saturable absorber fibre.
Dussardier, Bernard, Maria, Jerome, Peterka, P.   +2 more
core   +2 more sources

Laser-produced continua for absorption spectroscopy in the VUV and XUV [PDF]

, 1980
Recent work has shown that with appropriate targets, laser-produced plasmas provide clean essentially linefree continua suitable for absorption spectroscopy from 40 to 2000 Å.
Ballofet, Breton, Burgess, Cantu, Carroll, Carroll, Codling, Cole, Damany, Esteva, Garton, Mahajan, Mehlman-Balloffet, Mehlman-Balloffet, Mussetto, Wyart   +15 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Generation of Flat-Top Q-Switched Envelope Dissipative Soliton Resonance Pulse in Passively Mode-Locked Fiber Laser

IEEE Photonics Journal, 2020
We present demonstration of an erbium-doped fiber laser based on the nonlinear amplifying loop mirror mechanism, with a stable phenomenon of flat-top Q-switched mode-locked (FT-QML) dissipative soliton resonance (DSR) pulse, for the first time.
Long Han, Tianshu Wang, Runmin Liu, Wanzhuo Ma, Yiwu Zhao, Qiang Fu, Huilin Jiang   +6 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Post-compression of a Q-switched laser in a glass-rod multi-pass cell

JPhys Photonics
Q-switched lasers are compact, cost-effective, and highly pulse energy-scalable sources for nanosecond-scale laser pulses. The technology has been developed for many decades and is widely used in scientific, industrial and medical applications.
Peer Biesterfeld, Arthur Schönberg, Marc Seitz, Nayla Jimenez, Tino Lang, Marcus Seidel, Prannay Balla, Lutz Winkelmann, Jyothish K Sunny, Sven Fröhlich, Philip Mosel, Ingmar Hartl, Francesca Calegari, Uwe Morgner, Milutin Kovacev, Christoph M Heyl, Andrea Trabattoni   +16 more
doaj   +1 more source

Diode-pumped Alexandrite lasers in Q-switched and cavity-dumped Q-switched operation

Optics Express, 2016
We present the first study of Q-switched Alexandrite lasers under continuous-wave diode-pumping with operation up to 10 kHz repetition rates in TEM00, with spatial quality M2 1.15. With a pulsed-diode dual-end-pumped design, pulse energy is scaled to a record level of 3 mJ.
Thomas, GM, Minassian, A, Sheng, X, Damzen, MJ   +3 more
openaire   +4 more sources

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Tunable Passively-Synchronized 1-μm Q-Switched and 1.5-μm Gain-Switched Dual-Wavelength Fiber Laser Based on an Er/Yb Codoped Fiber

IEEE Photonics Journal, 2017
A wavelength-tunable passively-synchronized 1-μm Q-switched and 1.5-μm gain-switched dual-wavelength pulsed fiber laser has been demonstrated with a single gain fiber for the first time to our knowledge.
Chunyu Guo, Weiqi Liu, Shuangchen Ruan, Jun Yu, Yewang Chen, Peiguang Yan, Jinzhang Wang, Saurabh Jain, Ping Hua   +8 more
doaj   +1 more source