Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi +12 more
wiley +1 more source
Thermal Spin Coated PbS QD SWIR Imager for Non‐Invasive Glucose Monitoring
Thermal spin‐coating enables controlled film formation of PbS quantum dots, leading to denser packing, reduced defect‐assisted transport, and improved carrier extraction. The resulting photodetectors exhibit suppressed dark current, enhanced responsivity, and faster response.
Lei Rao +9 more
wiley +1 more source
Strain‐Modulated Reconfigurable Optical Information Processing in Flexible Graphene/PDMS
Graphene/PDMS—a stable, mechanically robust, and highly tunable flexible composite, exhibits excellent strain‐tunability. The spatial self‐phase modulation (SSPM) effect can be reversibly and continuously modulated by strain. A strain‐gated optical switch can be constructed, thereby realizing reconfigurable optical logic gates and reversible switching ...
Zexin Cui +13 more
wiley +1 more source
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li +7 more
wiley +1 more source
This study demonstrates a Bi2WO6/SrBi2Ta2O9 heterojunction where light‐driven ferroelectric polarization reversal couples with persistent photoconductivity, enabling exclusive NO2 selective room‐temperature sensing. The device achieves a two‐order‐of‐magnitude sensitivity enhancement over an unpolarized device, a sub‐ppb detection limit, and robust ...
Liping Tan +11 more
wiley +1 more source
Nonsurgical lower eyelid rejuvenation using a novel 1064-nm Nd:YAG laser with a 650- microsecond pulse duration. [PDF]
Yang YS +4 more
europepmc +1 more source
Proposed treatment options for combined nevi: report of two cases using combination therapy involving surgical excision and laser therapy. [PDF]
Nagai K, Yamagi Y, Mitsukawa N.
europepmc +1 more source
Nonlinear Optical Response of Tungsten Carbide Thin Film as Saturable Absorber at 1 μm and Its Application for Passively Q-Switched Nd:YAG Lasers. [PDF]
Zhang Z +8 more
europepmc +1 more source
Combined Laser Therapy for Post-sclerotherapy Hyperpigmentation Following Nicolau Syndrome: A Case Report. [PDF]
Alekseev N, Mishanina V.
europepmc +1 more source

