Results 61 to 70 of about 221,506 (173)

Sickle Cell Diastolic Cardiomyopathy and Mortality Risk: A Novel Echocardiographic Framework for Prognostic Stratification

American Journal of Hematology, Volume 100, Issue 11, Page 1940-1951, November 2025.
ABSTRACT Cardiovascular complications are the leading cause of mortality in sickle cell anemia (SCA) patients. While extensive data have identified diastolic dysfunction (DD) to increase morbidity and mortality, the unique hemodynamic conditions inherent to SCA challenge the current recommendations to assess diastolic function. Thus, there is an urgent
Théo Simon, Laurent Savale, Kristoffer Grundtvig Skaarup, Paul Breillat, Luu‐Ly Pham, Seyed‐Mehdi Nouraie, Niklas Dyrby Johansen, Jocelyn Inamo, Francois Lionnet, Gylna Loko, Christelle Chantalat, Anne Laure Pham Hung d’Alexandry d’Orengiani, Anoosha Habibi, Gonzalo de Luna, Sihem Iles, Frédéric Galactéros, Etienne Audureau, Tor Biering‐Sørensen, Pablo Bartolucci, Geneviève Derumeaux, Thomas d’Humières   +20 more
wiley   +1 more source

Low-cost desktop learning factory to support the teaching of artificial intelligence

HardwareX
The following document details low-cost hardware and open-source available software tools that can be combined to support active teaching methodologies like Problem-Based Learning (PBL) and incorporate work-oriented technological skills in students. This
Eduardo Orozco, Paulo C. Cárdenas, Jesús A. López, Cinthia K. Rodriguez   +3 more
doaj   +1 more source

hnRNP-Q1 represses nascent axon growth in cortical neurons by inhibiting Gap-43 mRNA translation

Molecular Biology of the Cell, 2016
A novel posttranscriptional mechanism for regulating the neuronal protein GAP-43 is reported. The mRNA-binding protein hnRNP-Q1 represses Gap-43 mRNA translation by a mechanism involving a 5′ untranslated region G-quadruplex structure, which affects GAP ...
K. Williams, Damian S. McAninch, Snezana Stefanovic, L. Xing, Megan Allen, Wenqi Li, Yue Feng, M. Mihailescu, G. Bassell   +8 more
semanticscholar   +1 more source

Cross‐Cultural Adaptation and Cross‐Validation of the Italian Version of the EPICC Spiritual Care Competency Self‐Assessment Tool for Clinical Nurses

Journal of Clinical Nursing, Volume 34, Issue 11, Page 4757-4768, November 2025.
ABSTRACT Aim To cross‐culturally adapt and psychometrically test the Italian version of the EPICC Spiritual Care Competency Self‐Assessment Tool for clinical nurses (EPICC Tool‐It). Design Multicentre, cross‐sectional validation study. Methods The 28‐item EPICC Tool was translated into Italian and culturally adapted following a rigorous methodology.
Michela Piredda, Alessio Lo Cascio, Maddalena De Maria, Roberto Latina, Anna Marchetti, Anna De Benedictis, Giorgia Petrucci, Linda Ross, Wilfred McSherry, Maria Grazia De Marinis   +9 more
wiley   +1 more source

Protocol for fiber photometry recording from deep brain regions in head-fixed mice

STAR Protocols
Summary: To exclude the influence of motion on in vivo calcium imaging, animals usually need to be fixed. However, the whole-body restraint can cause stress in animals, affecting experimental results. In addition, some brain regions are prone to bleeding
Siyao Zhou, Shumin Duan, Hongbin Yang
doaj   +1 more source

Cross‐Border Shopping of Alcohol—What is the Effect on Tax Revenue and Sales and Which Products Are Most Affected?

Review of International Economics, Volume 33, Issue 5, Page 1021-1034, November 2025.
ABSTRACT We use COVID‐19 border closings and comprehensive store‐level data on Norwegian alcohol sales to quantify the effect cross‐border shopping of alcohol on sales volume and commodity tax revenue. Effects are large, for instance, we estimate that commodity tax revenue for wine is about 20% lower because of cross‐border shopping.
Richard Friberg, Frode Steen, Simen A. Ulsaker   +2 more
wiley   +1 more source

Sample collection protocol for single-cell RNA sequencing of functionally identified neuronal populations in vivo

STAR Protocols
Summary: Here, we present a sample collection protocol for single-cell RNA sequencing of functionally identified neuronal populations in vivo with a virally delivered activity-dependent labeling tool (CaMPARI2).
Sean M. O’Toole, Georg B. Keller
doaj   +1 more source

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves, Darius Lane, Adam Wahida, Md. Jakaria, Pawel Kalinowski, Adam Southon, Abdel Ali Belaidi, Teresa Samperi‐Esteve, Triet Phu Minh Nguyen, Peng Lei, Marcus Krueger, Stefan Mueller, Marcus Conrad, Puja Agarwal, Sue E Leurgans, Julie Schneider, Ashley I. Bush, Scott Ayton   +17 more
wiley   +1 more source

Toward a personalized autonomous transportation system: Vision, challenges, and solutions

The Innovation
The fragmented design of intelligent transportation systems creates isolated intelligent systems. Resource competition and information gaps are fierce and widespread, worsening traffic issues and degrading overall service levels.
Linlin You, Mai Hao, Jian Sun, Yunpeng Wang, Chunming Rong, Chau Yuen, Paolo Santi, Carlo Ratti   +7 more
doaj   +1 more source

Translational upregulation of Aurora-A by hnRNP Q1 contributes to cell proliferation and tumorigenesis in colorectal cancer

Cell Death and Disease, 2017
By using RNA-immunoprecipitation assay following next-generation sequencing, a group of cell cycle-related genes targeted by hnRNP Q1 were identified, including Aurora-A kinase.
Chien-Hsien Lai, Yu-chuan Huang, Jenq‐Chang Lee, J. T. Tseng, Kung-Chao Chang, Yen-Ju Chen, N. Ding, Pao-Hsuan Huang, Wen-Chang Chang, B. Lin, R. Chen, Yu-Chu Wang, Yi-Chien Lai, Liang-Yi Hung   +13 more
semanticscholar   +1 more source