Results 121 to 130 of about 19,176 (234)

Spectrum of Hypogonadism and Its Management in Adolescents With Prader‐Willi Syndrome: A Retrospective Cohort Study Over 35 Years

Clinical Endocrinology, Volume 105, Issue 1, Page 51-59, July 2026.
ABSTRACT Context Adult data indicate that hypogonadism is underdiagnosed and undertreated in Prader‐Willi Syndrome (PWS). Objectives We aimed to describe the spectrum of pubertal development, and the diagnosis and treatment of hypogonadism in paediatric/adolescent patients with PWS. Design/Patients A retrospective cohort study of patients with PWS aged
Helen Nguyen, Geoffrey Ambler, Yoon Hi Cho   +2 more
wiley   +1 more source

Clinical Characteristics, Treatment Patterns, and Prognosis of Central Nervous System Involvement in Multiple Myeloma: A Multicenter Retrospective Study From China

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Central nervous system (CNS) involvement is a rare and aggressive complication of multiple myeloma (MM), with limited data on its clinical characteristics and prognosis. This multicenter study characterizes the largest Chinese cohort of MM patients with CNS involvement (MM‐CNS) to date.
Wenjing Li, Weiwei Tian, Jie Ma, Linyu Li, Zhihua Li, Jie Liu, Guorong Gao, Zhenfang Xi, Lan Zhang, Weihua Zhang, Lixiang Duan, Hui Geng, Jie Meng, Honghu Zhu, Wenming Chen, Wen Gao   +15 more
wiley   +1 more source

CIC–DUX4 Rearranged Gastric Sarcoma Confirmed by Next‐Generation Sequencing: A Case Report and Review of Literature

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT This case highlights that gastric CIC‐DUX4 rearranged sarcoma is highly aggressive and diagnostically challenging. Early comprehensive genomic profiling was essential for confirming this rare subtype. Despite transient responses to Ewing sarcoma regimens, rapid chemoresistance was observed, emphasizing the need for precise molecular diagnosis ...
Hiroko Hasegawa, Atsushi Takeno, Rei Higashiura, Yuko Sakakibara, Mizuki Koba, Yumiko Hirose, Kiyoshi Mori, Motohiro Hirao, Masayuki Mano, Ryotaro Sakamori   +9 more
wiley   +1 more source

Myeloid/lymphoid neoplasm with FLT3 gene fusion: report of a case with a novel t(5;13)(q13;q12) SSBP2::FLT3 fusion. [PDF]

J Hematop
Cook JR, Astbury C, Bosler DS, Molina JC, Rogers HJ, Sobecks RM, Owczarczyk AB.   +6 more
europepmc   +1 more source

CEBP and ZEB2 alterations define three distinct subtypes of B‐cell acute lymphoblastic leukemia

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract B‐cell acute lymphoblastic leukemia (B‐ALL) is a heterogeneous malignancy driven by diverse genetic alterations. Among these, CEBP family genes and ZEB2 are recurrently involved, yet the spectrum of genomic mechanisms and their clinical impact remain incompletely defined.
Rathana Kim, Marie Passet, Hugo Bergugnat, Loïc Vasseur, Thibaut Leguay, Françoise Huguet, Mathilde Hunault, Tom Sexton, Melha Benlebna, Julie Renard, Emmanuel Raffoux, Cédric Pastoret, Cathie Erb, Laureen Chat, Eric Delabesse, Stéphanie Gachet, Caroline Bonmati, Marie Balsat, Thorsten Braun, Audrey Bidet, Nicolas Duployez, Carlos Graux, Yves Chalandon, Philippe Rousselot, Patrice Chevallier, Jean Soulier, Véronique Lhéritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier   +29 more
wiley   +1 more source

Sperm whales habituate to research vessels engaged in photoidentification. [PDF]

PLoS One
Whitehead H, Clarke CMK, Eguiguren A.
europepmc   +1 more source

Effective Strategies to Reduce Anxiety in Patients Undergoing Cataract Surgery: An Umbrella Review

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Introduction Anxiety, which involves feelings of tension, worry, and physiological changes in the body, can have significant impacts on patients, including an increased risk of mortality. In ophthalmic surgeries, particularly cataract procedures, anxiety levels tend to be high, often stemming from fears of blindness or surgical failure.
Masoumeh Masoumy, Shahnaz Ahrari, Mehdi Rezaei   +2 more
wiley   +1 more source

Seasonal Variation and Genetic Evaluation of Needle Catechin Content in Half-Sib Families of <i>Pinus taeda</i>. [PDF]

Plants (Basel)
Sun J, Wang L, Liu T, Luo J, Gao C, Huang S, Zhang X, Yu J, Liu F, Cao L, Zhang Y, Liu C.   +11 more
europepmc   +1 more source

Dialogue Through Play: Games as a Bridge for Citizen Engagement

Journal of Computer Assisted Learning, Volume 42, Issue 3, June 2026.
ABSTRACT Background Digital games are increasingly used as tools for civic and societal engagement, particularly to reach younger and digitally literate publics on complex issues such as climate change. While such approaches can facilitate large‐scale participation and raise awareness, their capacity to support deliberative forms of civic engagement ...
Rebecca Harris, Paul Hollins, Anchal Garg, Pradeep Hewage, Paul Watson, Celestine Iwendi, Jude Ower, Joost Schuur   +7 more
wiley   +1 more source

Chronic myeloid leukemia in blast phase masquerading as T-lymphoblastic lymphoma with t(22;22) karyotype: a case report. [PDF]

Front Oncol
Liu Y, Hao Z, Bai J, Zhou W, Zhang H, Guan Z, Zhang L, Li L.   +7 more
europepmc   +1 more source