Results 31 to 40 of about 19,247 (234)

UBE3A Dosage Imbalance as a Molecular Framework Linking Angelman Syndrome and Dup15q‐Associated Autism Phenotypes

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT UBE3A is a dosage‐sensitive HECT E3 ubiquitin ligase whose neuronal expression is shaped by genomic imprinting at the 15q11.2‐q13 locus. Opposite directions of UBE3A dosage imbalance contribute to distinct neurodevelopmental phenotypes: loss of maternal UBE3A underlies Angelman syndrome, whereas maternally derived 15q11.2‐q13 copy‐number gains,
Ruslan Kurmashev
wiley   +1 more source

Strategic Categorization of Dairy Cow Farms in Croatia using Cluster Analysis

Business Systems Research
The milk processing sector in the Republic of Croatia faces numerous challenges. It is a distinctly bipolar structure, with some entities resembling the largest milk producers in the EU, while many small and medium-sized dairy farms struggle to remain ...
Petrač Maja, Zmaić Krunoslav, Žgajnar Jaka   +2 more
doaj   +1 more source

Effect of Bacillus paralicheniformis Q13 on Alleviating Hyperuricemia Induced by Potassium Oxonate in Mice [PDF]

Shipin Kexue
Objective: To find a novel probiotic strain capable of effectively alleviating hyperuricemia (HUA) and to validate its inhibitory effect on HUA in an animal model. Methods: All mice were randomly divided into four groups (n = 6 per group): control (CON),
SUO Linglan, LI Yue, JIANG Bin, LENG Yue, REN Dayong
doaj   +1 more source

Multivariate Analysis of Hematological Stress Biomarkers and Welfare Domains in Organic and Intensive Pig Farming in Italy: A Pilot Study

Animal Research and One Health, EarlyView.
Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito, Talal Hassan, Antonio Marco Maisano, Stefania Bergagna, Cecilia Guasco, Barbara Miniscalco, Martina Tarantola, Elena Colombino, Claudio Caruso, Ahsan Muhammad, Silvia Mioletti, Laura Tomassone, Massimiliano Tursi, Cristina Vercelli, Giovanni Loris Alborali, Maria Teresa Capucchio   +15 more
wiley   +1 more source

Prosocial behaviour in primary and secondary school students. Effects of the CYBUPRE intervention

British Educational Research Journal, EarlyView.
Abstract Prosocial behaviour is regarded as a critical factor in reducing aggressive behaviours among peers, both in physical settings and virtual spaces. This variable facilitates the enhancement of social relationships, promoting empathy, deep listening, physical and verbal service, and even solidarity, among other benefits.
Mercedes Chicote‐Beato, Ana Rosa Bodoque‐Osma, Fernando Martins, Sixto González‐Víllora   +3 more
wiley   +1 more source

Pathways to a Circular Economy in the Agriculture-Food System: Actor-Based Analysis of Digital Capacity, Institutional Alignment, and Collaboration Dynamics Using the EDDU-M Model

Zagadnienia Ekonomiki Rolnej
This study addresses the transition to a circular economy (CE) in agri-food supply chains, focusing on how digitalization, institutional capacity, and collaboration shape CE practices.
Ağizan Kemalettin, Ağizan Süheyla
doaj   +1 more source

Antibacterial Mechanism of Bacteriocin of Lactococcus lactis Q13 against Methicillin-Resistant Staphylococcus aureus [PDF]

Shipin Kexue
The antibacterial mechanism of bacteriocin produced by Lactococcus lactis Q13 against methicillin-resistant Staphylococcus aureus (MRSA) was investigated in this study.
LIU Shuang, WANG Jinli, LIANG Anjian, YANG Yangyang, ZHU Chenglin, TANG Junni
doaj   +1 more source

Supernumerary derivative 22 chromosome resulting from novel constitutional non-Robertsonian translocation: t(20;22)—Case Report

Molecular Cytogenetics, 2022
Background Maternal non-Robertsonian translocation-t(20;22)(q13;q11.2) between chromosomes 20 and 22resulting in an additional complex small supernumerary marker chromosome as derivative (22)inherited to the proband is not been reported yet.
H. C. Manju, Supriya Bevinakoppamath, Deepa Bhat, Akila Prashant, Jayaram S. Kadandale, P. V. V. Gowri Sairam   +5 more
doaj   +1 more source

Machine Learning‐Based PAT Tool for Real‐Time Residual Moisture Monitoring in Lyophilized Biopharmaceuticals Using NIR Spectroscopy

Biotechnology and Bioengineering, EarlyView.
ABSTRACT There is a growing demand in the pharmaceutical industry to optimize analytical methodologies, reducing time and resource consumption while ensuring rapid process development and cost‐efficient manufacturing. Indeed, Food and Drug Administration (FDA) introduced the Process Analytical Technology (PAT) as an initiative enabling manufacturers to
Samuele Fiorenza, Mariapia D'Urso, Ambra Massei, Nunzia Falco, Davide Fissore, Enza Torino   +5 more
wiley   +1 more source

t(2;19)(p12;q13) IGK/BCL3 - t(14;19)(q32;q13) IGH/BCL3 - t(19;22)(q13;q11) BCL3/IGL [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on t(2;19)(p12;q13) IGK/BCL3 - t(14;19)(q32;q13) IGH/BCL3 - t(19;22)(q13;q11) BCL3/IGL, with data on clinics, and the genes involved.
openaire   +2 more sources