Results 1 to 10 of about 10,105 (150)

Should the Workload of Combining Clinical Practice With Data Collection be Considered: A Survey of Physicians With Data Collection Experience. [PDF]

J Evid Based Med
ABSTRACT Aim To survey the physician's attention to the workload of combining clinical practice with Traditional Chinese Medicine (TCM) data collection. Background With the development of artificial intelligence technology in the medical field, the task of collecting diverse clinical data in TCM has increased.
Zhang X, Jiang Y, Guan Z, Zhao M, Hu M, Xu Q, Wang W, Gao W, Qiu R, Li M, Yang B, Zhou L, Liu Z, Li Z, Xiang Y, Zhao J, Wang Z, Lou X, Guo S, Dai G, Bian Z, Wang H, Zhao C, Shang H.   +23 more
europepmc   +2 more sources

Real-world lecanemab adoption in Japan 1 year after launch: Insights from 311 specialists on infrastructure and reimbursement barriers. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Lecanemab was approved for early Alzheimer's disease in Japan, with ≈ 6000 patients treated in the first year post approval. This study explores real‐world practices, challenges, and potential solutions. METHODS We conducted an anonymized online survey of clinical specialists authorized to prescribe lecanemab, obtaining responses ...
Sato K, Niimi Y, Ihara R, Iwata A, Nemoto K, Arai T, Higashi S, Igarashi A, Kasuga K, Akiyama H, Awata S, Ikeda M, Iwatsubo T.   +12 more
europepmc   +2 more sources

Barriers to Changing Sedation Practice for Patients Undergoing Mechanical Ventilation on the Intensive Care Unit: A Qualitative Interview Study of Clinical Staff. [PDF]

Nurs Crit Care
ABSTRACT Background Medical sedation is a requirement for mechanical ventilation for most patients admitted to the intensive care unit (ICU). Sedation can help minimise patient discomfort, pain and distress, but can lead to hypotension, bradycardia, prolonged ventilation and delirium.
Richards ND, Bekker HL, Howell SJ.
europepmc   +2 more sources

A functional helix shuffled variant of the B domain of Staphylococcus aureus. [PDF]

Protein Sci
Abstract The B domain of protein A is a biotechnologically important three‐helix bundle protein. It binds the Fc fragment of antibodies with helix 1/2 and the Fab region with helix 2/3. Here we designed a helix shuffled variant by changing the connectivity of the helices, in order to redesign the helix bundle, yielding altered helix–loop–helix ...
Bobolowski H, Fiedler E, Haupts U, Lilie H, Weininger U.   +4 more
europepmc   +2 more sources

Quantum trajectory analysis of a thresholdlike transition in the microlaser [PDF]

, 1997
In a recent microlaser experiment [K. An et al., Phys. Rev. Lett. 73, 3375 (1994)], a thresholdlike transition of intracavity mean photon number as a function of intracavity mean atom number has been observed.
An, Kyungwon, Yang, Changhuei
core   +1 more source

Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter baumannii [PDF]

, 2014
Acinetobacter baumannii is an important human pathogen that can form biofilms and persist under harsh environmental conditions. Biofilm formation and virulence are modulated by blue light, which is thought to be regulated by a BLUF protein, BlsA.
Adelbert Bacher, Agnieszka Gil, Allison Haigney, Andras Lukacs, Barth A., Bitrian M., Boris Illarionov, Brust R., Carlos Simmerling, Cheng-Tsung Lai, Decatur S. M., Gaddy J. A., Giamarellou H., Golic A., Gregory M. Greetham, Grinstead J. S., Haigney A., Haigney A., Hasegawa K., Hasegawa K., Ian P. Clark, Jung A., Kiri Addison, Kondo M., Losi A., Lukacs A., Markus Fischer, Masuda S., Masuda S., Masuda S., McQueary C. N., Michael Towrie, Mussi M. A., Pelton J. T., Peter J. Tonge, Richard Brust, Ryu-Ryun Kim, Shahrier Hossain, Stelling A. L., Stephen R. Meech, Suzuki H., Takahashi R., Wu Q., Yuan H., Yuan H., Yuan H.   +45 more
core   +2 more sources

Structural insights into how vacuolar sorting receptor recognizes the C‐terminal sorting determinant of a vicilin‐like seed storage protein

The FEBS Journal, Volume 293, Issue 1, Page 257-270, January 2026.
Soluble cargo proteins are sorted to the vacuoles via a receptor‐mediated mechanism. Combining crystallographic and mutagenesis studies, we showed how the C‐terminal sorting determinant (ctVSD) of vicilin‐like seed storage protein VL22 is recognized by the protease‐associated domain of Arabidopsis vacuolar‐sorting receptor 1.
Shu Nga Lui, Hsi‐En Tsao, Anthony Hiu‐Fung Lo, Liwen Jiang, Kam‐Bo Wong   +4 more
wiley   +1 more source

A Characterization of Wilson-Lerch Primes [PDF]

, 2015
This note presents criteria in terms of Bernoulli numbers for a prime to be simultaneously a Wilson prime and a Lerch prime.http://www.integers-ejcnt.org/q51/q51.Abstract ...
Dobson, John Blythe
core   +1 more source

Dissimilarities of reduced density matrices and eigenstate thermalization hypothesis

, 2017
We calculate various quantities that characterize the dissimilarity of reduced density matrices for a short interval of length $\ell$ in a two-dimensional (2D) large central charge conformal field theory (CFT).
He, Song, Lin, Feng-Li, Zhang, Jia-ju
core   +1 more source

Health‐Related Quality of Life in Patients With a Head and Neck Sarcoma: A Mixed‐Methods Study

Head &Neck, Volume 47, Issue 11, Page 3086-3097, November 2025.
ABSTRACT Background Patients with head and neck sarcomas (HNS) face unique health‐related quality of life (HRQoL) challenges due to its disease rarity. This study examined and identified the prevalence of generic‐ and location‐specific HRQoL issues.
E. Koffi, C. S. Padilla, C. Drabbe, W. H. Schreuder, C. Zemouri, D. den Hollander, D. J. Grünhagen, S. Sodergren, S. Singer, R. L. Jones, I. M. E. Desar, L. Fauske, M. Pinto, I. Nixon, S. Salah, Ø. S. Bruland, V. L. M. N. Soomers, M. A. J. van de Sande, J. J. de Haan, C. Verhoef, L. C. Steggink, W. J. van Houdt, T. I. Bootsma, M. T. Tesselaar, W. T. A. van der Graaf, O. Husson   +25 more
wiley   +1 more source