Commensal Bacteria Maintain a Qa-1b-restricted Unconventional CD8+ T Population in Gut Epithelium [PDF]
, 2023 Jian Guan +6 more
openalex +1 more source
Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System
Advanced Science, EarlyView.This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi +13 more
wiley +1 more source
Environment International, 2020 Background: Quinolinic acid (QA), a neuroactive metabolite produced during tryptophan degradation, is implicated in the pathogenesis of several neurological disorders. Phthalates are structurally similar to QA, and exposure to phthalates has demonstrated
Feiby L. Nassan, ScD, MBBCh, MSc +4 more
doaj +1 more source
Restructuring quality assurance frameworks: A comparative study between NIAD-QE in Japan and HEEACT in Taiwan [PDF]
Higher Education Evaluation and Development, 2018 Purpose - The purpose of this paper is to examine how the Japanese and Taiwanese national quality assurance (QA) agencies, National Institution for Academic Degrees and Quality Enhancement (NIAD-QE) and Higher Education Evaluation and Accreditation ...
Ayaka Noda +3 more
doaj +1 more source
Question Answering on Linked Data: Challenges and Future Directions
, 2016 Question Answering (QA) systems are becoming the inspiring model for the future of search engines. While recently, underlying datasets for QA systems have been promoted from unstructured datasets to structured datasets with highly semantic-enriched ...
Endris, Kemele +6 more
core +1 more source
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Advanced Science, EarlyView.Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Análisis espacial y temporal de Q-Coda en el Piedemonte Llanero (Colombia)
Earth Sciences Research Journal, 2002 <p class="MsoNormal" style="line-height: normal; margin: 0cm 0cm 0pt; mso-layout-grid-align: none;"><span style="font-family: ";Arial";,";sans-serif";; font-size: 12pt; mso-ansi-language: EN-US;" lang="EN-US">The space-time variation of the ...
Duran Juan P. +2 more
doaj
Holistic QA: Software Quality Assurance for the Machine Learning Era [PDF]
, 2023 Shane Downing, M. Affan Badar
openalex +1 more source
Advanced Science, EarlyView.This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou +17 more
wiley +1 more source
Impact of arteriovenous fistula blood flow on serum il-6, cardiovascular events and death: An ambispective cohort analysis of 64 Chinese hemodialysis patients. [PDF]
PLoS ONE, 2017 Flows (Qa) of arteriovenous fistula (AVF) impact the dialysis adequacy in hemodialysis (HD) patients. However, data for different access flow levels on outcomes related to long-term dialysis patients, especially in Chinese patients, are limited.
Zhizhi Hu +16 more
doaj +1 more source