Results 11 to 20 of about 217,775 (241)

Diagnostic accuracy of SPECT/CT in parathyroid adenoma detection: impact of radiopharmaceutical choice and quality control practices [PDF]

open access: yesEJNMMI Reports
Purpose To evaluate the diagnostic accuracy of SPECT/CT for localizing parathyroid adenomas and to determine how radiopharmaceutical choice (MIBI vs.
Badriah Alasmari   +4 more
doaj   +2 more sources

Quality-control (QC) performance measures and the QC planning process [PDF]

open access: yesClinical Chemistry, 1997
Abstract Numerous outcome measures can be used to characterize and compare the performance of alternative quality-control (QC) strategies. The performance measure traditionally used in the QC planning process is the probability of rejecting an analytical run when a critical out-of-control error condition exists.
openaire   +2 more sources

Effects of Quality Control Targets (SpO2≠100%, PaCO2/<40 mmHg, Pmean/>10 cmH2O) on Outcomes in Patients in the ICU

open access: yesFrontiers in Medicine, 2020
Objectives: A series of quality control (QC) targets (SpO2≠100%, PaCO2≮40 mmHg, Pmean≯10 cmH2O) was put forward and widely used in a single intensive care unit (ICU) setting.
Pan Pan   +6 more
doaj   +1 more source

Setting up an own laboratory performance-based internal quality control plan - a model for complete blood count

open access: yesRomanian Journal of Laboratory Medicine, 2022
Quality Control (QC) in Romania is regulated by the Order of the Minister of Health no. 1608/2022 that modifies the previous Order 1301/2007. The new version of the Order introduces a more scientific approach by requesting the laboratories to assess test
Oprea Oana R.   +3 more
doaj   +1 more source

Meta-QC-Chain: Comprehensive and Fast Quality Control Method for Metagenomic Data

open access: yesGenomics, Proteomics & Bioinformatics, 2014
Next-generation sequencing (NGS) technology has revolutionized and significantly impacted metagenomic research. However, the NGS data usually contains sequencing artifacts such as low-quality reads and contaminating reads, which will significantly ...
Qian Zhou   +3 more
doaj   +1 more source

Improving quality of transcutaneous bilirubin measurements: Value of in-house developed quality control

open access: yesPractical Laboratory Medicine, 2021
Objectives: Quality assurance (QA) plays an integral role in Point of Care Testing (POCT) programs. Quality control (QC) is an important QA program component to ensure high quality results and enhanced patient care.
Heather Anne Paul   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data

open access: yesBMC Genomics, 2018
Background RNA-Seq has become one of the most widely used applications based on next-generation sequencing technology. However, raw RNA-Seq data may have quality issues, which can significantly distort analytical results and lead to erroneous conclusions.
Qian Zhou   +4 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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