Results 21 to 30 of about 739,334 (261)

Meta-QC-Chain: Comprehensive and Fast Quality Control Method for Metagenomic Data

Genomics, Proteomics & Bioinformatics, 2014
Next-generation sequencing (NGS) technology has revolutionized and significantly impacted metagenomic research. However, the NGS data usually contains sequencing artifacts such as low-quality reads and contaminating reads, which will significantly ...
Qian Zhou, Xiaoquan Su, Gongchao Jing, Kang Ning   +3 more
doaj   +1 more source

Improving quality of transcutaneous bilirubin measurements: Value of in-house developed quality control

Practical Laboratory Medicine, 2021
Objectives: Quality assurance (QA) plays an integral role in Point of Care Testing (POCT) programs. Quality control (QC) is an important QA program component to ensure high quality results and enhanced patient care.
Heather Anne Paul, Brenda Joanne Adams, Allison Anne Venner   +2 more
doaj   +1 more source

A partial differential equation for the strictly quasiconvex envelope

, 2016
In a series of papers Barron, Goebel, and Jensen studied Partial Differential Equations (PDE)s for quasiconvex (QC) functions \cite{barron2012functions, barron2012quasiconvex,barron2013quasiconvex,barron2013uniqueness}. To overcome the lack of uniqueness
Abbasi, Bilal, Oberman, Adam M.
core   +1 more source

Quantum pathology of static internal imperfections in flawed quantum computers [PDF]

, 2007
Even in the absence of external influences the operability of a quantum computer (QC) is not guaranteed because of the effects of residual one- and two-body imperfections.
Alicki, Anastopoulos, Benenti, Brown, Caldeira, Caldeira, Dawson, Feingold, Feynman, Fortunato, Frahm, Gaspard, Georgeot, Georgeot, Giulini, Haake, Hairer, Joshua Wilkie, Lehoucq, Loss, Lucamarini, Ma, Monasterio, Murat Çetinbaş, Nakajima, Nielsen, Paganelli, Pechukas, Prokof'ev, Prosen, Prosen, Prosen, Romero-Rochin, Romero-Rochin, Romero-Rochin, Suárez, Tessieri, Weinstein, Wilkie, Wilkie, Wilkie, Wilkie, You, Yuan, Yuan, Zwanzig, Çetinbaş, Žnidarič   +47 more
core   +1 more source

Adiabatic Cluster State Quantum Computing

, 2010
Models of quantum computation are important because they change the physical requirements for achieving universal quantum computation (QC). For example, one-way QC requires the preparation of an entangled "cluster" state followed by adaptive measurement ...
Bacon, Dave, Flammia, Steven T.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data

BMC Genomics, 2018
Background RNA-Seq has become one of the most widely used applications based on next-generation sequencing technology. However, raw RNA-Seq data may have quality issues, which can significantly distort analytical results and lead to erroneous conclusions.
Qian Zhou, Xiaoquan Su, Gongchao Jing, Songlin Chen, Kang Ning   +4 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Glutaminyl cyclase activity correlates with levels of Aβ peptides and mediators of angiogenesis in cerebrospinal fluid of Alzheimer’s disease patients

Alzheimer’s Research & Therapy, 2017
Background Pyroglutamylation of truncated Aβ peptides, which is catalysed by enzyme glutaminyl cyclase (QC), generates pE-Aβ species with enhanced aggregation propensities and resistance to most amino-peptidases and endo-peptidases.
Claire Bridel, Torsten Hoffmann, Antje Meyer, Sisi Durieux, Marleen A. Koel-Simmelink, Matthias Orth, Philip Scheltens, Inge Lues, Charlotte E. Teunissen   +8 more
doaj   +1 more source