Results 41 to 50 of about 1,863,949 (262)

Biotechnological Approaches to Optimize the Production of Amaryllidaceae Alkaloids

Biomolecules, 2022
Amaryllidaceae alkaloids (AAs) are plant specialized metabolites with therapeutic properties exclusively produced by the Amaryllidaceae plant family. The two most studied representatives of the family are galanthamine, an acetylcholinesterase inhibitor ...
Manoj Koirala, Vahid Karimzadegan, Nuwan Sameera Liyanage, Natacha Mérindol, Isabel Desgagné-Penix   +4 more
doaj   +1 more source

Genetically Programmed Shape‐Morphing of Engineered Living Materials

Advanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker, Yuchen Liu, Miguel Baños, Rosanne Schmachtenberg, Mahmudul Hasan, Claudia Fink‐Straube, Luai R. Khoury, Wilfried Weber   +7 more
wiley   +1 more source

Antimicrobial activity and chemical composition of white birch (Betula papyrifera Marshall) bark extracts

MicrobiologyOpen, 2020
Extracts from white birch have been reported to possess antimicrobial properties, but no study has linked the chemical composition of bark extract with antimicrobial activity.
Dorian Blondeau, Annabelle St‐Pierre, Nathalie Bourdeau, Julien Bley, André Lajeunesse, Isabel Desgagné‐Penix   +5 more
doaj   +1 more source

Utilizing the Metastability of Spidroins as a Strategy for Improving Mechanical Properties of Biomimetic Spider Silk Fibers

Advanced Functional Materials, EarlyView.
Phase transitions are central for the assembly of recombinant silk proteins into fibers. Soluble protein can transition into condensed states such as condensates and gels. These states are metastable and evolve in a time‐dependent way. Metastability depends on the protein sequence, and this relationship can be used to enhance the mechanical properties ...
Fred‐Eric Sammalisto, Topias Lankinen, Celine Tallroth, Rafael A. Lara, Matilda Backholm, Markus B. Linder   +5 more
wiley   +1 more source

Recent Conceptual Consequences of Loop Quantum Gravity. Part I: Foundational Aspects. [PDF]

, 2001
Conceptual consequences of recent results in loop quantum gravity are collected and discussed here in view of their implications for a modern philosophy of science which is mainly understood as one that totalizes scientific insight so as to eventually ...
Zimmermann, Rainer E.
core  

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

Advanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu, Mahboobeh Mahmoodi, Ehsanul Hoque Apu, Fahimeh Shahabipour, Sibel Emir Diltemiz, Sanjib Saha, Halima Alem, Nureddin Ashammakhi   +7 more
wiley   +1 more source

Nuclear Physics for Cultural Heritage [PDF]

, 2016
Nuclear physics applications in medicine and energy are well known and widely reported. Less well known are the many important nuclear and related techniques used for the study, characterization, assessment and preservation of cultural heritage.
The Nuclear Physics Division of the European Physical Society
core  

Cell‐Free DNA as a Biomarker of Cell Death and Treatment Response for On‐Chip Three‐Dimensional Tumor Models

Advanced Healthcare Materials, EarlyView.
This study presents quantifying cell‐free DNA (cfDNA) as a non‐disruptive and rapidly quantifiable method for assessing cell death for on‐chip 3D sarcoma tumor models. On‐chip cfDNA release reflects tumor burden, extent of cell death, and survival of in vitro and ex vivo 3D models, providing valuable insight into the temporal response of tumor models ...
Maryam Ziaee, Julie Lafontaine, Badr Id Said, Kousha Kamal, Kim Tsoi, Francis Rodier, Thomas Gervais, Philip Wong   +7 more
wiley   +1 more source

FeynTune: large language models for high-energy theory

Machine Learning: Science and Technology
We present specialized large language models (LLMs) for theoretical high-energy physics, obtained as 20 fine-tuned variants of the 8 billion parameter Llama-3.1 model.
Paul Richmond, Constantinos Papageorgakis, Vasilis Niarchos, Borun Chowdhury, Prarit Agarwal   +4 more
doaj   +1 more source

Estimating retinal blood oxygenation from diffuse reflectance spectra of semi-infinite tissue using principal component analysis

Frontiers in Photonics
Diffuse reflectance spectroscopy (DRS) is a promising technique for non-invasive monitoring of tissue oxygen saturation (StO2). However, the interpretation of DRS data can be complicated by the presence of confounding factors such as the volume fraction ...
Elahe Parham, Elahe Parham, Jonathan Munro, Nicolas Lapointe, Patricia Landry, Jonathan Robidoux, Danny Brouard, Mireille Quémener, Mireille Quémener, Martin Parent, Dominic Sauvageau, Dominic Sauvageau, Daniel C. Côté, Daniel C. Côté, Cléophace Akitegetse   +14 more
doaj   +1 more source