Results 21 to 30 of about 74,061 (70)

Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold

Molecules
The antiapoptotic BAG3 protein plays a crucial role in cellular proteostasis and it is involved in several signalling pathways governing cell proliferation and survival. Owing to its multimodular structure, it possesses an extensive interactome including
Dafne Ruggiero, Emis Ingenito, Eleonora Boccia, Vincenzo Vestuto, Maria Rosaria Miranda, Stefania Terracciano, Gianluigi Lauro, Giuseppe Bifulco, Ines Bruno   +8 more
doaj   +1 more source

Investigation of the Frying Fume Composition During Deep Frying of Tempeh Using GC-MS and PTR-MS

Molecules
This study employed proton transfer reaction mass spectrometry (PTR-MS) and gas chromatography–mass spectrometry (GC-MS) to identify and monitor volatile organic compounds (VOCs) in frying fumes generated during the deep frying of tempeh.
Rohmah Nur Fathimah, Tomasz Majchrzak
doaj   +1 more source

Alkaloids with Their Protective Effects Against Aβ_25-35-Induced PC-12 Cell Injury from the Tubers of Pinellia pedatisecta Schott

Molecules
Seven new alkaloids [1, (±)-2, (±)-3, 4, and 5] and one new natural product (6), along with eight known analogues, were isolated from the tubers of Pinellia pedatisecta Schott. Their structures were determined by a comprehensive analysis of spectroscopic
Xu Chen, Yangang Cao, Kaili Ye, Yanling Liu, Fangge Chi, Ying Niu, Di Lu, Bingxian Zhao, Lan Chen, Xiaoke Zheng, Weisheng Feng   +10 more
doaj   +1 more source

Determination of Photosensitizing Potential of Lapachol for Photodynamic Inactivation of Bacteria

Molecules
Antimicrobial photodynamic inactivation (aPDI) offers a promising alternative to combat drug-resistant bacteria. This study explores the potential of lapachol, a natural naphthoquinone derived from Tabebuia avellanedae, as a photosensitizer (PS) for aPDI.
Regiane G. Lima, Raphael S. Flores, Gabriella Miessi, Jhoenne H. V. Pulcherio, Laís F. Aguilera, Leandro O. Araujo, Samuel L. Oliveira, Anderson R. L. Caires   +7 more
doaj   +1 more source

Azobenzene as an Effective Ligand in Europium Chemistry—A Synthetic and Theoretical Study

Molecules
The preparation and characterization of two novel europium–azobenzene complexes that demonstrate the effectiveness of this ligand for stabilizing reactive, redox-active metals are reported.
Damian G. Allis, Ana Torvisco, Cody C. Webb, Miriam M. Gillett-Kunnath, Karin Ruhlandt-Senge   +4 more
doaj   +1 more source

The Ordered Structures Formed by Janus-like Particles on a Triangular Lattice

Molecules
The formation of ordered structures by Janus-like particles, composed of two parts (A and B), with orientation-dependent interactions on a triangular lattice was studied using Monte Carlo methods. The assumed lattice model allows each particle to take on
Andrzej Patrykiejew
doaj   +1 more source

The Composition, Antioxidant and Antibacterial Activity of Essential Oils from Five Species of the Magnoliaceae Family

Molecules
The leaves of Magnoliaceae family plants contain abundant essential oils (EOs), and these species can be used in many fields due to their high industrial, medicinal, and ornamental values.
Dandan Yang, Daocheng Ma, Ziqi Song, Mei Yang, Yuanyuan Xu   +4 more
doaj   +1 more source

Synthesis and Evaluation of a ZnO-Chitosan Adduct for Safe and Sustainable Enhanced Ultra-Violet (UV) Sunscreens Protection

Molecules
Chitosan (Ch), a natural polysaccharide, is known for its biocompatibility, biodegradability, and various beneficial properties, including antioxidant and antibacterial activities.
Mattia Battistin, Alessandro Bonetto, Francesco Nicoli, Elena Torreggiani, Andrea Brunetta, Elena Cesa, Stefano Manfredini, Anna Baldisserotto, Silvia Vertuani   +8 more
doaj   +1 more source

Synergistic Combination of Quercetin and Mafosfamide in Treatment of Bladder Cancer Cells

Molecules
Bladder cancer, which has a rising incidence, is the 10th most common cancer. The transitional cell carcinoma histotype is aggressive and often current therapies are ineffective.
Carmela Spagnuolo, Francesco Mautone, Anna Maria Iole Meola, Stefania Moccia, Giuseppe Di Lorenzo, Carlo Buonerba, Gian Luigi Russo   +6 more
doaj   +1 more source

iTRAQ-Based Proteomic Profiling of Skin Aging Protective Effects of Tremella fuciformis-Derived Polysaccharides on D-Galactose-Induced Aging Mice

Molecules
In the present study, a heteromannan primarily composed of mannose, fucose, xylose, glucose, and arabinose at a molar ratio of 4.78:1.18:1:0.82:0.11 containing a low proportion of glucuronic acid with weight-average molecular weights of 3.6 × 106 Da ...
Yuanyuan Xu, Xiaofei Liu, Jingjing Guan, Jin Chen, Xiaofei Xu   +4 more
doaj   +1 more source