Results 31 to 40 of about 72,730 (77)

Unveiling Vibrational Couplings in Model Peptides in Solution by a Theoretical Approach

Molecules
Vibrational analysis of peptides in solution and the theoretical determination of the effects of the microenvironment on infrared and Raman spectra are of key importance in many fields of chemical interest.
Federico Coppola, Fulvio Perrella, Alessio Petrone, Greta Donati, Luciana Marinelli, Nadia Rega   +5 more
doaj   +1 more source

Integration Viewpoint Using UHPLC-MS/MS, In Silico Analysis, Network Pharmacology, and In Vitro Analysis to Evaluate the Bio-Potential of Muscari armeniacum Extracts

Molecules
The current study investigates the chemical profiling, antioxidant activities, and enzyme inhibitory and cytotoxic potential of the water and methanolic extracts of different parts (flower, leaf, and bulb) of Muscari armeniacum.
Nilofar Nilofar, Gokhan Zengin, Mehmet Veysi Cetiz, Evren Yildiztugay, Zoltán Cziáky, József Jeko, Claudio Ferrante, Tina Kostka, Tuba Esatbeyoglu, Stefano Dall’Acqua   +9 more
doaj   +1 more source

Synthesis, characterization, conformational study, and antioxidant activity of N-acylhydrazone derivatives [PDF]

A series of N-acylhydrazone derivatives (SB 1-SB 8) were successfully synthesized in yields ranging from 68% to 97% through the condensation of a carboxylic acid hydrazide with various benzaldehydes bearing different substituents.
Lee, Charles Kuok Sui
core  

One-Pot Synthesis of Novel Pyrimidine Derivatives with Potential Antidiabetic Activity Through Dual α-Glucosidase and α-Amylase Inhibitors

Molecules
This study describes the synthesis of heterocyclic derivatives containing multiple nitrogen atoms serving as important moieties for developing novel antidiabetics through a simple synthetic pathway.
Ohood Al-Shehri, Samar Abubshait, Muhammad Nawaz, Mohamed S. Gomaa, Haya A. Abubshait   +4 more
doaj   +1 more source

Synthesis of Novel Tetra-Substituted Pyrazole Derivatives Using Microwave Irradiation and Their Anti-Leukemic Activity Against Jurkat Cells

Molecules
Three previously synthesized ketene dithioacetals were used as intermediates to obtain four nucleophiles to synthesize ten tetra-substituted pyrazoles (11–20).
Felipe P. Machado, Maria Clara Campos, Juliana Echevarria-Lima, Diego P. Sangi, Carlos Serpa, Otávio Augusto Chaves, Aurea Echevarria   +6 more
doaj   +1 more source

Phytochemical Screening and Biological Activities of Lippia multiflora Moldenke

Molecules
Lippia multiflora Moldenke is widely used in Angola, on the African continent, and beyond for the treatment of many health conditions such as hypertension, enteritis, colds, gastrointestinal disturbances, stomachaches, jaundice, coughs, fevers, nausea ...
Dorcas Tlhapi, Ntsoaki Malebo, Idah Tichaidza Manduna, Monizi Mawunu, Ramakwala Christinah Chokwe   +4 more
doaj   +1 more source

Strategies Used for the Discovery of New Microbial Metabolites with Antibiotic Activity

Molecules
The discovery of new microbial metabolites is essential to combat the alarming rise in antimicrobial resistance and to meet emerging medical needs. This work critically reviews current strategies for identifying antimicrobial compounds, emphasizing the ...
Pablo Dasí-Delgado, Cecilia Andreu, Marcel·lí del Olmo   +2 more
doaj   +1 more source

Natural Low-Eutectic Solvent Co-Culture-Assisted Whole-Cell Catalyzed Synthesis of Ethyl (R)-4-Chloro-3-Hydroxybutyrate

Molecules
In this study, CGMCC NO:28566, a strain that can efficiently convert Ethyl 4-chloroacetoacetate(COBE) to (R)-4-chloro-3-hydroxybutyrate((R)-CHBE), was screened by soil-sieving bacteria.
Yanni Wang, Bo Liu, Yanmei Dai, Zijuan Tao, Lan Tang, Zhimin Ou   +5 more
doaj   +1 more source

Targeting Ocular Biofilms with Plant-Derived Antimicrobials in the Era of Antibiotic Resistance

Molecules
Microbial biofilms present a formidable challenge in ophthalmology. Their intrinsic resistance to antibiotics and evasion of host immune defenses significantly complicate treatments for ocular infections such as conjunctivitis, keratitis, blepharitis ...
Monika Dzięgielewska, Michał Tomczyk, Adrian Wiater, Aleksandra Woytoń, Adam Junka   +4 more
doaj   +1 more source

Novel Magnetically Recoverable Amino-Functionalized MIL-101(Fe) Composite with Enhanced Adsorption Capacity for Pb(II) and Cd(II) Ions

Molecules
In this study, we report the synthesis and characterization of a novel NH2-MIL-101(Fe) magnetic composite, developed via in situ formation of NH2-MIL-101(Fe) in the presence of Fe3O4 nanoparticles embedded within a chloropropyl-modified mesoporous silica
Claudia Maria Simonescu, Daniela C. Culita, Gabriela Marinescu, Irina Atkinson, Virgil Marinescu, Ovidiu Oprea, Nicolae Stanica   +6 more
doaj   +1 more source