Results 51 to 60 of about 56,475 (99)

CircRNA circ‐IQGAP1 Knockdown Alleviates Interleukin‐1β‐Induced Osteoarthritis Progression via Targeting miR‐671‐5p/TCF4

Orthopaedic Surgery, 2021
To explore the function of circular RNA IQ motif‐containing GTPase‐activating protein 1 (circ‐IQGAP1) in interleukin (IL)‐1β‐induced osteoarthritis (OA) model and to explore whether circ‐IQGAP1 can modulate microRNA‐671‐5p (miR‐671‐5p) and transcription ...
Peng Xi, Cailin Zhang, Shizhong Wu, Lei Liu, Wenbo Li, Yimei Li   +5 more
semanticscholar   +1 more source

Nrf2 attenuates ferroptosis-mediated IIR-ALI by modulating TERT and SLC7A11

Cell Death and Disease, 2021
Acute lung injury (ALI) carries a mortality rate of ~50% and is a hot topic in the world of critical illness research. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a critical modulator of intracellular oxidative homeostasis and serves as an ...
Hui Dong, Yangyang Xia, Shanliang Jin, Chaofan Xue, Yanjun Wang, Rong Hu, Hong Jiang   +6 more
doaj   +1 more source

MicroRNA-671-5p inhibits cell proliferation, migration and invasion in non-small cell lung cancer by targeting MFAP3L

Molecular Medicine Reports, 2021
MicroRNA (miR)-671-5p serves as a tumor suppressor in several types of cancer, including gastric and breast cancer. However, the function of miR-671-5p in non-small cell lung cancer (NSCLC) has not been described in detail.
Junhui Ye, Wujun Luo, Lingling Luo, Limin Zhai, P-L Huang   +4 more
semanticscholar   +1 more source

USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1

Cell Death and Disease, 2021
PD-L1(CD274) is a well-known immunosuppressive molecule, which confers immunoescape features to cancer cells and has become one of the major targets in cancer immunotherapies.
Jinghua Pan, Yiting Qiao, Congcong Chen, Hongjing Zang, Xiaojing Zhang, Feng Qi, Cunjie Chang, Fan Yang, Mengqing Sun, Shengbin Lin, Quandong Tang, Lina Li, Menglan Wang, Minjie Wu, Yongzhu Liu, Caiyong Lai, Jianxiang Chen, Guo Chen   +17 more
doaj   +1 more source

LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer

Cell Death and Disease, 2021
Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and development in bladder cancer. However, the underlying molecular mechanisms remain elusive.
Wenjie Luo, Jun Wang, Wenhao Xu, Chunguang Ma, Fangning Wan, Yongqiang Huang, Mengfei Yao, Hailiang Zhang, Yuanyuan Qu, Dingwei Ye, Yiping Zhu   +10 more
doaj   +1 more source

miR-671-5p Inhibition by MSI1 Promotes Glioblastoma Tumorigenesis via Radioresistance, Tumor Motility and Cancer Stem-like Cell Properties

Biomedicines, 2021
MicroRNAs (miRNAs) could be potential biomarkers for glioblastoma multiforme (GBM) prognosis and response to therapeutic agents. We previously demonstrated that the cancer stem cell marker Musashi-1 (MSI1) is an RNA binding protein that promotes ...
Jang-Chun Lin, C. Kuo, J. Tsai, Wei-Hsiu Liu   +3 more
semanticscholar   +1 more source

Correction: Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations

Cell Death and Disease, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Tingting Sui, Li Xu, Yeh Siang Lau, Di Liu, Tingjun Liu, Yandi Gao, Liangxue Lai, Renzhi Han, Zhanjun Li   +8 more
doaj   +1 more source

A gene toolbox for monitoring autophagy transcription

Cell Death and Disease, 2021
Autophagy is a highly dynamic and multi-step process, regulated by many functional protein units. Here, we have built up a comprehensive and up-to-date annotated gene list for the autophagy pathway, by combining previously published gene lists and the ...
Matteo Bordi, Rossella De Cegli, Beatrice Testa, Ralph A. Nixon, Andrea Ballabio, Francesco Cecconi   +5 more
doaj   +1 more source

CAMELS-GB: hydrometeorological time series and landscape attributes for 671 catchments in Great Britain

Earth System Science Data, 2020
. We present the first large-sample catchment hydrology dataset for Great Britain, CAMELS-GB (Catchment Attributes and MEteorology for Large-sample Studies).
G. Coxon, N. Addor, J. Bloomfield, J. Freer, M. Fry, J. Hannaford, N. Howden, Rosanna A. Lane, M. Lewis, E. Robinson, T. Wagener, R. Woods   +11 more
semanticscholar   +1 more source

Circ_0000620 acts as an oncogenic factor in gastric cancer through regulating MMP2 expression via sponging miR-671-5p

Journal of Biological Research, 2021
Background Gastric cancer (GC) is one of the most common cancers in the digestive system. Circular RNAs (circRNAs) have been found to function as important regulators in the pathogenesis of GC.
Junyu Ren, G-Q Pan, Jun Yang, N. Xu, Qiong Zhang, Wenliang Li   +5 more
semanticscholar   +1 more source