Results 81 to 90 of about 462 (153)

Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia   +7 more
wiley   +1 more source

Chinese Registry on Transjugular Intrahepatic Portosystemic Shunts (CN‐TIPS): Protocol for a Registry‐Based, Prospective Prognostic Study

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
CN‐TIPS is a nationwide, multicenter prospective registry that will enroll 10,000 adults with portal hypertension undergoing transjugular intrahepatic portosystemic shunt in China, integrating perioperative clinical and hemodynamic metrics with standardized imaging (including computational modeling in a dedicated subcohort) and multi‐omics biospecimens,
Yi Xiang   +20 more
wiley   +1 more source

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

open access: yesPhytotherapy Research, EarlyView.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng   +8 more
wiley   +1 more source

Autonomous Navigation in Large‐Scale Underground Environments Based on a Purely Topological Understanding of Tunnel Networks

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT This work presents a non‐geometrical navigation approach based on a purely topological understanding of underground environments. By conceptualizing subterranean scenarios as a set of tunnels that intersect with each other, and taking a navigation approach based on topological instructions, we simplify the navigation problem to the sequential ...
Lorenzo Cano   +2 more
wiley   +1 more source

Biomimetic Multifinger Tactile Sensing and Contact‐Regulated Palpation for Autonomous Breast Tumor Localization

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Early detection of breast abnormalities remains challenging: manual palpation is subjective and operator‐dependent, while imaging modalities may miss small or subtle stiffness anomalies. This paper presents a biomimetic multifinger robotic palpation approach intended to support early breast‐cancer screening and follow‐up assessment as a proof ...
Kai Cheng   +7 more
wiley   +1 more source

Identification of initial vegetation and habitat changes in small temperate fens using remote sensing

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Temperate fens with only incipient, subtle signs of deterioration can be reliably identified using Sentinel‐2 and aerial imagery, which sensitively detect early productivity‐related structural changes. Abstract Small temperate fens rank among the most endangered habitats in temperate Europe.
Lubomír Tichý   +9 more
wiley   +1 more source

Advancing SDG7–SDG13 Through Technology Innovation: The Environmental Impacts of Technological Advancements in Green, Fossil, and Energy Efficiency in Türkiye

open access: yesSustainable Development, EarlyView.
ABSTRACT Identifying the principal drivers of carbon emissions is vital for designing effective mitigation strategies and supporting long‐term environmental sustainability. Although previous studies have explored multiple determinants of emissions, limited attention has been paid to the most influential energy–technology channels within trade‐dependent
Gang Kou   +3 more
wiley   +1 more source

Hybrid Multiphoton Lithography Scaffolds for Nanoscale Mechanobiological Assessment in Microscale Bone Models

open access: yesSmall, EarlyView.
This work presents a 3D hybrid tissue scaffold inspired by bone, incorporating collagen, fabricated using multiphoton lithography. The mechanical properties of collagen are tunable, and biodegradation allows for time‐dependent changes in geometry. The results demonstrate enhanced osteogenic differentiation of stem cells in our hybrid scaffolds.
Christoph Naderer   +7 more
wiley   +1 more source

Greenway development and gentrification

open access: yesSouthern Economic Journal, EarlyView.
Abstract This paper presents research on expanding access to green spaces in developed areas. Critics claim greenway projects lead to gentrification by increasing the demand for housing and pushing out residents in nearby neighborhoods. We look for evidence of this phenomenon using a sorting model and panel data on aggregate populations in Atlanta ...
Jarron VanCeylon, Richard T. Melstrom
wiley   +1 more source

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