Results 101 to 110 of about 3,934 (296)

Qi stagnation and qi deficiency are associated with depression in college students

Frontiers in Public Health
ObjectiveThe current study aims to investigate the correlations between qi stagnation, qi deficiency, and depression levels among college students.MethodThis study investigated 403 college students and measured their levels of depression, qi stagnation, and qi deficiency to analyze the relationship between these three variables. Pearson correlation and
Wang Xinzhu, Huang Yuanchun
openaire   +3 more sources

Process quality indicators for chronic kidney disease risk management: a systematic literature review

, 2016
Background and objectivesQuality indicators (QIs) can be used for measuring the quality of actions of healthcare providers. This systematic review gives an overview of such QIs measuring processes of care for chronic kidney disease (CKD), and identifies ...
Petra Denig, Denig, Petra, Bouma, Margriet, Sidorenkov, Grigory; id_orcid, Kirsten P.J. Smits, Margriet Bouma, Sidorenkov, Grigory, Grigory Sidorenkov, Navis, Gerjan J., Denig, Petra; id_orcid, Bilo, Henk J. G., Smits, Kirsten P. J., Gerjan J. Navis, Henk J.G. Bilo   +13 more
core   +1 more source

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Defining quality indicators for heart failure in general practice

, 2018
Background: Quality indicators (QIs) are used to measure and evaluate quality of care. However, QIs to evaluate care for HF patients in general practice in Belgium are lacking.
Marie Smets (5798765), Bert Aertgeerts (827702), Van den Bulck, Steve, Vaes, Bert, Steve Van den Bulck (5798771), Aertgeerts, Bert, Miek Smeets (5798768), Smeets, Miek, Stefan Janssens (390984), Bert Vaes (3413906), Smets, Marie, Janssens, Stefan   +11 more
core   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

Advanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy   +8 more
wiley   +1 more source

Basel II and Developing Countries: Sailing through the Sea of Standards [PDF]

Despite recently announced delays, Basel II - the new standard for bank capital - is due to be completed this year for implementation in the 13 Basel Committee member countries by the end of 2006.
Andrew Powell
core   +2 more sources

Fructose‐Based Single‐Chain Polymer Nanoparticles for GLUT1–Mediated Delivery: Impact of Polymer Design on Uptake and In Vivo Performance

Advanced Healthcare Materials, EarlyView.
Single‐chain nanoparticles have been proposed as drug delivery carriers, but adding a tail can significantly enhance their performance. This was demonstrated using a tadpole‐like structure comprising a head prepared from a UV‐crosslinked fructose‐based glycopolymer capable of targeting GLUT receptors, combined with a PEG‐based tail. Compared with other
Hoang Yen Vo, Linqing Tian, Qiaoyun Wang, Evelyn Szabo, Rebecca Y. Lai, Fariba Dehghani, Martina H. Stenzel   +6 more
wiley   +1 more source

Quality indicators for safe and effective use of medications in long-term care settings: A systematic review. [PDF]

Br J Clin Pharmacol
People accessing aged care services are increasingly older and often experience multimorbidity and polypharmacy, which puts them at risk of medication‐related harm.
Gutteridge DS, Calder AH, Stasinopoulos J, Javanparast S, Caughey GE, Hillen JB, Stafford AC, Peterson GM, Inacio MC, Khadka J, Kalisch Ellett LM, Jackson SL, Hibbert PD, Cations ML, Corlis ME, Yu SC, Clark MJ, Soulsby NR, Manias E, Yoo GH, Sluggett JK.   +20 more
europepmc   +2 more sources

Gellan Gum Fluid Gel System for Controlled‐Delivery of Cytokine‐Licensed MSC‐EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency

Advanced Healthcare Materials, EarlyView.
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh, Ava Dashti, Thomas E. Robinson, Robyn Gaffey, Richard Moakes, Neil Lagali, Liam Grover, Thomas Ritter   +7 more
wiley   +1 more source