Results 211 to 220 of about 3,934 (296)

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Effect of exercise training in patients with cardiac sarcoidosis after induction of oral corticosteroid therapy. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Yanagi H, Konishi H, Shimada Y, Miura H, Aoki T, Noguchi T.   +5 more
europepmc   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan, Hongmei Yang, Renfei Wu, Meng Hao, Xiangpeng Chu, Chuxia Deng, Kathy Qian Luo   +6 more
wiley   +1 more source

Effect of Neuromuscular Electrical Stimulation for Older Critically Ill Patients in the ICU: A Randomized Controlled Trial. [PDF]

Crit Care Explor
Yokobatake K, Kitaoka H, Morizane A, Kashima K, Nishimori D, Nishimura S, Sakyo Y, Takeuchi S, Kawano Y, Sugimura T.   +9 more
europepmc   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

Real-World Infective Endocarditis in a Regional Hospital: Clinical Severity, Guideline Adherence, and Determinants of In-Hospital Outcomes. [PDF]

J Clin Med
Pop C, Pop LL, Petruș MR, Talpos AI, Hodas R, Pop L, Pop I.   +6 more
europepmc   +1 more source

Surface Fermi Level Modulation of Photoanode by Optimized Conducting Nanoparticle Heterointerfaces for Enhanced Photoelectrochemical Water Splitting

Advanced Science, EarlyView.
Optimizing the heterointerface coverage of the conducting Ni2P nanoparticles on the surface of BVO photoanode manipulates the surface Fermi‐level modulation, which significantly enhances photoelectrochemical oxygen evolution reaction. Our multiscale simulations and experimental results reveal that an optimal Ni2P coverage of 9.4% pins the surface Fermi
Phuong Thi Pham, Seulgi Ji, Unbeom Baeck, Yuankai Li, Duong Nguyen Nguyen, Won Tae Hong, Yang You, John Moraros, Kyoungsuk Jin, Jun Young Lee, Chan‐Hwa Chung, Tae‐Hoon Kim, Jongwook Park, Heechae Choi, Jung Kyu Kim   +14 more
wiley   +1 more source

Improvement of Cancer Care-Analysis of ESGO Quality Indicators for the Surgical Treatment of Endometrial Cancer in Slovenian and Croatian Gynaecologic Oncology Departments. [PDF]

Medicina (Kaunas)
Pakiž M, Klarić M, Dovnik A, Primorac GS, Knez J, Despot Đ, Al Mahdawi L, Pranjic M, Brumec A, Turković T, Cokan A.   +10 more
europepmc   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

Development of a quantitative self-assessment tool for hospital antimicrobial stewardship and infection control programs: a step towards standardizing clinical studies. [PDF]

JAC Antimicrob Resist
Zanichelli V, Zakariah SZ, Classen AY, Dumpis U, Giske CG, Goepel S, Hagen D, Jorgensen SB, Kessel J, Kjellander C, Kleppe LKS, Simonsen GS, Vehreschild MJGT, Vehreschild JJ, Semret M, PILGRIM Study Group .   +15 more
europepmc   +1 more source