Assessing Age-Associated Influences on Paramagnetic and Diamagnetic Susceptibility Maps in Postmortem Human Brains. [PDF]
We applied the APART‐QSM method to in situ postmortem MRI from 47 subjects (31–91 years) to assess age effects on paramagnetic and diamagnetic susceptibility. Diamagnetic susceptibility declined with age in basal ganglia, possibly reflecting shared biological factors.
de Azevedo JHM +7 more
europepmc +2 more sources
Evaluation of Brain Microstructural Alterations in Preschool Autism Spectrum Disorder: A Voxel-Wise Multimodal MRI Study. [PDF]
ABSTRACT Background Autism Spectrum Disorder (ASD) presents with early neurodevelopmental alterations in preschool children, yet comprehensive characterization using multimodal quantitative MRI remains limited in this age group. Purpose To investigate voxel‐wise brain microstructural differences in preschool ASD through integrated analysis of cerebral ...
Wang C +7 more
europepmc +2 more sources
Quantitative Susceptibility Mapping in Skull Base Chordoma: In Silico Analysis and In Vivo Application Towards Indirect Hypoxia Assessment. [PDF]
ABSTRACT Purpose To evaluate quantitative susceptibility mapping (QSM) beyond the brain through realistic simulations and to explore preliminary evidence that may be indicative of hypoxia in skull base chordomas (SBC). Methods Each step of the QSM pipeline was optimized within an in silico framework consisting of (i) phase unwrapping, (ii) background ...
Fenech P +8 more
europepmc +2 more sources
Mapping Intracellular Volume Fraction With Susceptibility Source Decomposition as a Marker for Tissue Cellularity. [PDF]
ABSTRACT Background Pathophysiological changes affect tissue cell composition and density. For example, neurodegenerative disorders and brain tumors are associated with cell loss and abnormal accumulation, respectively. In these scenarios, if monitored and tracked, tissue cellularity might be used to inform clinical diagnosis and management. Purpose To
Debiasi G +7 more
europepmc +2 more sources
Incomplete spectrum QSM using support information
IntroductionReconstructing a bounded object from incomplete k-space data is a well posed problem, and it was recently shown that this incomplete spectrum approach can be used to reconstruct undersampled MRI images with similar quality to compressed sensing approaches.
Fuchs, Patrick, Shmueli, Karin
openaire +4 more sources
Quicksilver Scalable Multicast (QSM) [PDF]
QSM is a multicast engine designed to support a style of distributed programming in which application objects are replicated among clients and updated via multicast. The model requires platforms that scale in dimensions previously unexplored; in particular, to large numbers of multicast groups. Prior systems werenpsilat optimized for such scenarios and
Krzysztof Ostrowski +2 more
openaire +1 more source
Iterative Restoration of the Fringe Phase (REFRASE) for QSM [PDF]
In quantitative susceptibility mapping (QSM), reconstructed results can be critically biased by misinterpreted or missing phase data near the edges of the brain support originating from the non-local relationship between field and susceptibility. These data either have to be excluded or corrected before further processing can take place.
Johannes Lindemeyer +6 more
openaire +5 more sources
QSM Reconstruction Challenge 2.0: Design and Report of Results [PDF]
AbstractPurposeThe aim of the second quantitative susceptibility mapping (QSM) reconstruction challenge (Oct 2019, Seoul, Korea) was to test the accuracy of QSM dipole inversion algorithms in simulated brain data.MethodsA two-stage design was chosen for this challenge.
Berkin Bilgic +5 more
openaire +4 more sources
PurposeHomodyne filtering is a standard preprocessing step in the estimation of SWI. Unfortunately, SWI is not quantitative, and QSM cannot be accurately estimated from filtered phase images. Compared with gradient‐echo sequences suitable for computing QSM, SWI is more readily available and is often the only susceptibility‐sensitive sequence acquired ...
Vincent Beliveau +4 more
openaire +2 more sources
Feasibility of QSM in the human placenta
PurposeQuantitative susceptibility mapping (QSM) is an emerging tool for the precise characterization of human tissue, including regional oxygenation. A critical function of the human placenta is oxygen transfer to the developing fetus, which remains difficult to study in utero.
Zungho Zun +6 more
openaire +2 more sources

