Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies [PDF]
, 2012 To identify loci affecting the electrocardiographic QT interval, a measure of cardiac repolarisation associated with risk of ventricular arrhythmias and sudden cardiac death, we conducted a meta-analysis of three genome-wide association studies (GWAS ...
Arking, Dan E. +35 more
core +1 more source
Recent heart rate history affects QT interval duration in atrial fibrillation. [PDF]
PLoS ONE, 2017 QT interval prolongation is associated with a risk of polymorphic ventricular tachycardia. QT interval shortens with increasing heart rate and correction for this effect is necessary for meaningful QT interval assessment.
Fady S Riad +4 more
doaj +1 more source
QT Interval Changes in Moderate and Severe Brain Injuries [PDF]
, 2012 Backgrounds: Traumatic brain injuries are common mortality causes in many countries. Electrocardiogram (ECG) changes after brain injuries are known, and among them alteration of QT interval is common.
Abbasi Fard, Salman. +4 more
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QT Indexes in Cirrhotic Patients: Relationship with Clinical Variables and Potential Diagnostic Predictive Value. [PDF]
, 2015 BACKGROUND AND AIMS: A wide spectrum of cardiovascular changes characterizes cirrhosis, ranging from subclinical alterations to hyperkinetic syndrome.
BUTTA', Carmelo +11 more
core +1 more source
A Common Genetic Variant Risk Score is Associated with Drug-Induced QT Prolongation and Torsade de Pointes Risk: A Pilot Study. [PDF]
, 2017 Background -Drug-induced QT interval prolongation, a risk factor for life-threatening ventricular arrhythmias, is a potential side effect of many marketed and withdrawn medications.
Behr, ER +11 more
core +2 more sources
Coffee, alcohol, smoking, physical activity and QT interval duration: results from the Third National Health and Nutrition Examination Survey. [PDF]
PLoS ONE, 2011 Abnormalities in the electrocardiographic QT interval duration have been associated with an increased risk of ventricular arrhythmias and sudden cardiac death.
Yiyi Zhang +5 more
doaj +1 more source
Sex and Rate Change Differences in QT/RR Hysteresis in Healthy Subjects
Frontiers in Physiology, 2022 While it is now well-understood that the extent of QT interval changes due to underlying heart rate differences (i.e., the QT/RR adaptation) needs to be distinguished from the speed with which the QT interval reacts to heart rate changes (i.e., the so ...
Irena Andršová +10 more
doaj +1 more source
Measurement and interpretation of electrocardiographic QT intervals in murine hearts. [PDF]
, 2014 Alterations in ECG QT intervals correlate with the risk of potentially fatal arrhythmias, for which transgenic murine hearts are becoming increasingly useful experimental models. However, QT intervals are poorly defined in murine ECGs.
Fraser, James A +4 more
core +2 more sources
Evaluation of differences in automated QT/QTc measurements between Fukuda Denshi and Nihon Koden systems. [PDF]
PLoS ONE, 2014 Automatic measurement becomes a preference, and indeed a necessity, when analyzing 1000 s of ECGs in the setting of either drug-inducing QT prolongation screening or genome-wide association studies of QT interval.
Motoaki Sano +7 more
doaj +1 more source
Bedaquiline Correlation to QT Interval Prolongation in DR-TB Patients
Jurnal Respirasi, 2022 Introduction: The regimen of drug-resistant tuberculosis (DR-TB) is Bedaquiline. One of the adverse events is QT interval prolongation, which can increase the risk of Torsade de Pointes (TdP) and lead to death. DR-TB patient screening before starting the
Vandu Primadana +2 more
doaj +1 more source