Results 41 to 50 of about 59,149 (179)

Thoracic epidural analgesia prolongs postoperative QT interval on electrocardiogram in major non-cardiac surgery: a randomized comparison and a prospective cohort analysis

open access: yesFrontiers in Pharmacology, 2023
Introduction: Prolongation of QT interval on electrocardiogram can be associated with perioperative lethal arrhythmia. Epidural analgesia is a commonly used modality to relieve surgical pain by blocking sensory nerves, which also blocks the autonomic ...
Kotaro Hori   +7 more
doaj   +1 more source

QT PRODACT: In Vivo QT Assay With a Conscious Monkey for Assessment of the Potential for Drug-Induced QT Interval Prolongation

open access: yesJournal of Pharmacological Sciences, 2005
In safety pharmacology studies, the effects on the QT interval of electrocardiograms are routinely assessed using a telemetry system in cynomolgus monkeys. However, there is a lack of integrated databases concerning in vivo QT assays in conscious monkeys.
Kentaro Ando   +12 more
doaj   +1 more source

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]

open access: yes, 2012
Background: The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti- inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.
Juhász Viktor   +36 more
core   +1 more source

Haloperidol affects coupling between QT and RR intervals in guinea pig isolated heart

open access: yesJournal of Pharmacological Sciences, 2019
Prolonged QT interval is an independent risk factor for development of ventricular arrhythmias. Haloperidol is one of the drugs inducing QT prolongation.
Petr Vesely   +8 more
doaj   +1 more source

Transient Long QT Development in a Patient with Takotsubo Cardiomyopathy

open access: yesJournal of Cardiovascular Emergencies, 2016
QT interval prolongation on the electrocardiogram is considered a precursory sign for imminent, potentially lethal ventricular arrhythmias. Beside the inherited condition of long QT syndrome, numerous drugs, certain electrolyte disturbances and early ...
Czuriga Dániel   +10 more
doaj   +1 more source

Diabetes mellitus attenuates the repolarization reserve in mammalian heart

open access: yes, 2007
Objective: In diabetes mellitus several cardiac electrophysiological parameters are known to be affected. In rodent experimental diabetes models changes in these parameters were reported, but no such data are available in other mammalian species ...
Lengyel, Csaba Attila   +12 more
core   +1 more source

Evaluation of Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio in patients with acute pancreatitis

open access: yesActa Medica Alanya, 2020
Aim: Acute pancreatitis may affect cardiovascular system regardless of etiology. Electrocardiographic parameters such as QT interval, corrected QT interval (QTc), Tp-e interval and Tp-e/QT, Tp-e/QTc ratio can be used to evaluate myocardial repolarization.
Yilmaz Güler, Can Ramazan Öncel
doaj   +1 more source

Sistema para análise da variabilidade de sinais fisiológicos: aplicação em variabilidade da frequência cardíaca e intervalo QT [PDF]

open access: yes, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia ElétricaReguladas pela automaticidade intrínseca do nodo sinoatrial e pela influência modulatória do Sistema Nervoso Autônomo, as
Petry, Daiana
core  

Prevalence and Determinants of QT Interval Prolongation in Medical Inpatients

open access: yes, 2012
QT interval prolongation carries an increased risk of torsade de pointes and ...
D. Aujesky   +20 more
core   +1 more source

Estimation of cardiac QTc intervals in people prescribed antipsychotics: a comparison of correction factors

open access: yesTherapeutic Advances in Psychopharmacology, 2022
Background: A prolonged electrocardiogram (ECG) QT interval is associated with cardiac events and increased mortality. Antipsychotics can prolong the QT interval.
Teodora Andric   +7 more
doaj   +1 more source

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