Results 21 to 30 of about 59,149 (179)

Increased vulnerability of human ventricle to re-entrant excitation in hERG-linked variant 1 short QT syndrome [PDF]

, 2011
The short QT syndrome (SQTS) is a genetically heterogeneous condition characterized by abbreviated QT intervals and an increased susceptibility to arrhythmia and sudden death.
Hancox Jules C., McPate, Mark J., Mark J McPate, Hancox, Jules C., Witchel, HJ, Witchel Harry J., Witchel, Harry J., Ismail Adeniran, Zhang, H., Hancox, JC, McPate, MJW, Henggui Zhang (74233), Ismail Adeniran (192479), Adeniran, I., Adeniran, Ismail, Zhang Henggui, Adeniran Ismail, Zhang, Henggui, Henggui Zhang, Jules C Hancox, Harry Witchel (4462174), Jules C Hancox (16149998), McPate Mark J., Mark J McPate (16150001), Harry J Witchel   +24 more
core   +1 more source

Effect of age and gender on QT interval

National Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: The sudden cardiac death syndrome has a large preponderance in men compared to women and that too in older age group. Various population studies have demonstrated four- to seven-fold increase of sudden cardiac death among men compared with ...
Sudeep Satpathy, Smita Satpathy, Prakash Kumar Nayak   +2 more
doaj   +1 more source

Recent heart rate history affects QT interval duration in atrial fibrillation. [PDF]

PLoS ONE, 2017
QT interval prolongation is associated with a risk of polymorphic ventricular tachycardia. QT interval shortens with increasing heart rate and correction for this effect is necessary for meaningful QT interval assessment.
Fady S Riad, Eathar Razak, Samir Saba, Alaa Shalaby, Jan Nemec   +4 more
doaj   +1 more source

Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database [PDF]

, 2013
Background: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US ...
MORETTI, Ugo, De Ponti F., Sturkenboom, M, Sturkenboom, M.C.J.M. (Miriam), De Ponti, F, Behr, E.R. (Elijah), Koci A, Spina, E, Sturkenboom M, Ariola Koci, Poluzzi E, Spina E, Raschi, E. (Emanuel), Ponti, F. (Fabrizio) de, Ugo Moretti, Spina, E. (Edoardo), Poluzzi, E, POLUZZI, ELISABETTA, Koci, A. (Ariola), Behr ER, Koci, A, Elijah R. Behr, Elisabetta Poluzzi, Poluzzi, E. (Elisabetta), Sturkenboom, MCJM, Moretti, U. (Ugo), Fabrizio De Ponti, KOCI, ARIOLA, Moretti, U, Emanuel Raschi, Raschi, E, Miriam Sturkenboom, DE PONTI, FABRIZIO, Moretti U, RASCHI, EMANUEL, Behr, ER, Raschi E, Edoardo Spina   +37 more
core   +1 more source

Coffee, alcohol, smoking, physical activity and QT interval duration: results from the Third National Health and Nutrition Examination Survey. [PDF]

PLoS ONE, 2011
Abnormalities in the electrocardiographic QT interval duration have been associated with an increased risk of ventricular arrhythmias and sudden cardiac death.
Yiyi Zhang, Wendy S Post, Darshan Dalal, Elena Blasco-Colmenares, Gordon F Tomaselli, Eliseo Guallar   +5 more
doaj   +1 more source

Sex and Rate Change Differences in QT/RR Hysteresis in Healthy Subjects

Frontiers in Physiology, 2022
While it is now well-understood that the extent of QT interval changes due to underlying heart rate differences (i.e., the QT/RR adaptation) needs to be distinguished from the speed with which the QT interval reacts to heart rate changes (i.e., the so ...
Irena Andršová, Katerina Hnatkova, Martina Šišáková, Ondřej Toman, Peter Smetana, Katharina M. Huster, Petra Barthel, Tomáš Novotný, Georg Schmidt, Marek Malik, Marek Malik   +10 more
doaj   +1 more source

Evaluation of differences in automated QT/QTc measurements between Fukuda Denshi and Nihon Koden systems. [PDF]

PLoS ONE, 2014
Automatic measurement becomes a preference, and indeed a necessity, when analyzing 1000 s of ECGs in the setting of either drug-inducing QT prolongation screening or genome-wide association studies of QT interval.
Motoaki Sano, Yoshiyasu Aizawa, Yoshinori Katsumata, Nobuhiro Nishiyama, Seiji Takatsuki, Shigeo Kamitsuji, Naoyuki Kamatani, Keiichi Fukuda   +7 more
doaj   +1 more source

Bedaquiline Correlation to QT Interval Prolongation in DR-TB Patients

Jurnal Respirasi, 2022
Introduction: The regimen of drug-resistant tuberculosis (DR-TB) is Bedaquiline. One of the adverse events is QT interval prolongation, which can increase the risk of Torsade de Pointes (TdP) and lead to death. DR-TB patient screening before starting the
Vandu Primadana, Indra Yovi, Dyah Siswanti Estiningsih   +2 more
doaj   +1 more source

[QT Interval and Its Prolongation - What Does It Mean?]

, 2020
The assessment of the QT interval has been an integral part of ECG interpretation since the first descriptions of long QT syndrome by Wolff in 1950 and by Jervell and Lange-Nielsen in 1957.
Castiglione, Alessandro, Odening, Katja
core   +1 more source

Integration of genetics into a systems model of electrocardiographic traits using humanCVD BeadChip [PDF]

, 2012
<p>Background—Electrocardiographic traits are important, substantially heritable determinants of risk of arrhythmias and sudden cardiac death.</p> <p>Methods and Results—In this study, 3 population-based cohorts (n=10 526) genotyped ...
Nelson, C.P., Whittaker, John, Kumari, Meena, Folkersen, Lasse, Lasse Folkersen, Drenos, F., Drenos, Fotios, Kumari, M., Nelson, Christopher P, Amuzu, A., Mika Kivimaki, Nilesh J. Samani, Braund, P.S., Folkersen, L., Whittaker, J., Juan-Pablo Casas, John Whittaker, Eriksson, Per, Burton, P.R., Christopher P. Nelson, Meena Kumari, Zhang, H., Tom R. Gaunt, Debbie A. Lawlor, Casas, J.-P., Peter S. Braund, Adeniran, Ismail, Samani, Nilesh J, Sonia Shah, Samani, N.J., Antoinette Amuzu, Amuzu, Antoinette, Humphries, S.E., Zhang, Henggui, Henggui Zhang, Philippa J. Talmud, Day, I.N.M., Hancox, Jules C, Hancox, J.C., Tomaszewski, M., Hingorani, Aroon D, Burton, Paul R, Maciej Tomaszewski, Lawlor, D.A., Jules C. Hancox, Ian N.M. Day, Steve E. Humphries, Kivimaki, Mika, Kivimaki, M., Tobin, Martin D, Lawlor, Debbie A, Hingorani, A.D., Per Eriksson, Eriksson, P., Tomaszewski, Maciej, Peter W. Macfarlane, Humphries, Steve E, Shah, S., Ismail Adeniran, Day, Ian NM, Macfarlane, P.W., Martin D. Tobin, Paul R. Burton, Day, Ian N M, Gaunt, Tom R, Macfarlane, Peter W, Adeniran, I., Fotios Drenos, Shah, Sonia, Talmud, Philippa J, Gaunt, T.R., Tobin, M.D., Casas, Juan-Pablo, Talmud, P.J., Braund, Peter S, Tomaszewski, Maciej; id_orcid, Aroon D. Hingorani   +76 more
core   +1 more source