Results 111 to 120 of about 24,231 (256)

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li, Yanwu Yang, Yan Zhang, Jirong Yue, Birong Dong, Meiling Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +7 more
wiley   +1 more source

Effects of adjunctive pimavanserin and current antipsychotic treatment on QT interval prolongation in patients with schizophrenia. [PDF]

Front Psychiatry, 2022
Bugarski-Kirola D, Nunez R, Odetalla R, Liu IY, Turner ME.   +4 more
europepmc   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

Journal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams, Les N. Harris, Jean‐Sébastien Moore, Ella K. Middleton, Shira A. Berkelhammer, Ben Speers‐Roesch, Matthew J. H. Gilbert   +6 more
wiley   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Concurrent Use of Tasipimidine Oral Solution and Fluoxetine in Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This exploratory randomized crossover study investigated pharmacokinetic interactions, functional alertness, and cardiovascular safety of tasipimidine oral solution administered alone and in combination with fluoxetine in healthy Beagle dogs (n = 8; 4 dogs per dose level), with a 7‐day washout between phases. Dogs received single oral doses of
Jenni Lindstedt, Jouko M. Levijoki, Johanna Tuunainen, Jens Häggström, Meri Ramela, Mira Korpivaara   +5 more
wiley   +1 more source

QT Interval Evaluation in Right Ventricular Pacing: Validation of a Novel Formula

Pacing and Clinical Electrophysiology, EarlyView.
Abstract Background QT interval measurement in the presence of right ventricular pacing (RVP) represents a clinical challenge. We therefore aimed to derive and validate a formula for QT estimation during RVP in a large cohort of pacemaker patients. Methods and Results We prospectively enrolled 100 patients in a derivation cohort and 487 in a validation
Amr Abdin, Alhasan Almasri, Ibrahim Antoun, Charles Gieres, Christian Werner, Yvonne Bewarder, Christian Ukena, Igor Schwantke, Michael Böhm, Saarraaken Kulenthiran   +9 more
wiley   +1 more source

QT INTERVAL PROLONGATION IS A NOVEL PREDICTOR OF 1-YEAR MORTALITY IN PATIENTS WITH COVID-19 INFECTION [PDF]

J Am Coll Cardiol, 2022
Banai A, Szekely Y, Lupu L, Borohovitz A, Levi E, Ghantous E, Taieb P, Hochstadt A, Banai S, Topilsky Y, Chorin E.   +10 more
europepmc   +2 more sources

Salbutamol-Induced QT Interval Prolongation in a Two-Year-Old Patient. [PDF]

Cureus, 2022
Elgassim M, Abdelrahman A, Saied ASS, Ahmed AT, Osman M, Hussain M, AlJaufi I, Salem W.   +7 more
europepmc   +1 more source

Left Bundle Branch Area Pacing Reverts Electromechanical Window Negativity to a Similar Extent as Biventricular Pacing

Pacing and Clinical Electrophysiology, EarlyView.
BiVP = biventricular pacing; CRT = cardiac resynchronization therapy; EMW = electromechanical window; LBBAP = left bundle branch area pacing; QAoC = Time interval from the onset of the QRS complex to the center of the aortic valve closure artifact; QT = QT interval measured by tangent method.
Florien Klein, Metra Daliry, Karin C. Smits, Edoardo Bressi, Peter M. Deissler, Johan van Koll, Jesse H. J. Rijks, Antonius M. W. van Stipdonk, Rachel M. A. ter Bekke, Domenico Grieco, Chiara Manfuro, Giorgia Spiridigliozzi, Annalisa Casalese, Justin G. L. M. Luermans, Frits W. Prinzen, Roel Meiburg, Leonard M. Rademakers, Kevin Vernooy, Uyên Châu Nguyên   +18 more
wiley   +1 more source

QT interval prolongation and heart failure severity: A longitudinal study. [PDF]

Bioinformation
Pandey MS, Shankar Pandey JM.
europepmc   +1 more source