Results 51 to 60 of about 73,159 (323)

Screening for QT Prolongation in the Emergency Department: Is There a Better “Rule of Thumb?” [PDF]

, 2020
Introduction: Identification of QT prolongation in the emergency department (ED) is critical for appropriate monitoring, disposition, and treatment of patients at risk for torsades de pointes (TdP).
Friedman, Ari B., Rischall, Megan L., Smith, Stephen W.   +2 more
core  

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source

QT Interval Prolongation Among Patients with Chronic Liver Disease Attending Jimma Medical Center Gastroenterology Clinic, Southwest Ethiopia

Research Reports in Clinical Cardiology, 2022
Tadelle Amanuel, Banjaw Zelalem Department of Biomedical Sciences, Jimma University, Jimma City, EthiopiaCorrespondence: Tadelle Amanuel, Email newaman09@yahoo.com; amanuel.muluneh@ju.edu.etBackground: Liver disease affects the electrophysiology of the ...
Amanuel T, Zelalem B
doaj  

Tailored Core‐Shell Nanocarrier for Therapeutic Drug Delivery via Visible Light Activation

Angewandte Chemie, EarlyView.
A core‐shell nanocarrier activated by visible light, composed of poly(3‐octylthiophene‐2,5‐diyl) (POT), iron oxide (II, III) (Fe3O4), polyvinyl alcohol (PVA), and trazodone tetraphenylborate (TRZ+ TPB−). During POT photooxidation (POT+), TRZ+ is liberated driven by the maintenance of particle's electroneutrality.
Deric Andrade‐Alarcón, Víctor de la Asunción‐Nadal, Gastón A. Crespo, María Cuartero   +3 more
wiley   +2 more sources

Association between C-reactive protein, corrected QT interval and presence of QT prolongation in hypertensive patients

Kaohsiung Journal of Medical Sciences, 2014
C-reactive protein (CRP) and corrected QT (QTc) interval are predictors of cardiovascular disease. Whether CRP is associated with QTc interval and QT prolongation is unknown in hypertensive patients.
Kai-Ting Chang, Hsu-Shien Shu, Chun-Yuan Chu, Wen-Hsien Lee, Po-Chao Hsu, Ho-Ming Su, Tsung-Hsien Lin, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu   +9 more
doaj   +1 more source

Scoping review: QT interval prolongation in regimen containing bedaquiline and delamanid in patients with drug-resistant tuberculosis

International Journal of Mycobacteriology, 2022
Background: A regimen containing bedaquiline–delamanid is recommended in management of drug-resistant tuberculosis (DR TB) to increase a success rate.
Oki Nugraha Putra, Yulistiani Yulistiani, Soedarsono Soedarsono   +2 more
doaj   +1 more source

The Effects of Trimetazidine on QT-interval Prolongation and Cardiac Hypertrophy in Diabetic Rats

Arquivos Brasileiros de Cardiologia, 2019
Background Trimetazidine (TMZ) is an anti-ischemic drug. In spite of its protective effects on cardiovascular system, there is no scientific study on the usefulness of TMZ treatment for prolonged QT interval and cardiac hypertrophy induced by diabetes ...
Fatemeh Ramezani-Aliakbari, M. Badavi, M. Dianat, S. Mard, A. Ahangarpour   +4 more
semanticscholar   +1 more source

Identification of Patients At-Risk of QT Interval Prolongation during Medication Reviews: A Missed Opportunity?

Journal of Clinical Medicine, 2018
The prolongation of the QT interval is a relatively rare but serious adverse drug reaction. It can lead to torsade de pointes, which is potentially life-threatening.
V. Buss, Kayla Lee, M. Naunton, G. Peterson, S. Kosari   +4 more
semanticscholar   +1 more source

Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias [PDF]

, 2016
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered for use under the comprehensive in vitro proarrhythmia assay (CiPA).
Blinova, Ksenia, Brock, Mathew, Chan, Dulciana, Chvatal, Stacie, Crumb, William J., Galeotti, Loriano, Hortigon-Vinagre, Maria P., Johannesen, Lars, Lyn-Cook, Beverly, Millard, Daniel, Pang, Li, Ross, James, Smith, Godfrey, Stockbridge, Norman, Stohlman, Jayna, Strauss, David G., Vicente, Jose, Zamora Rodriguez, Victor   +17 more
core   +1 more source

Drug-induced QT interval prolongation in cancer patients

Oncology Reviews, 2011
Cancer patients are at an increased risk for QT interval prolongation and subsequent potentially fatal Torsade de pointes tachycardia due to the multiple drugs used for treatment of malignancies and the associated symptoms and complications.
Torben K. Becker, Sai-Ching J. Yeung
doaj   +1 more source