Results 71 to 80 of about 24,231 (256)

Effects of L- and N-Type Ca Channel Blocker Cilnidipine on Changes in Heart Rate and QT Interval During Dialysis

Kidney & Blood Pressure Research, 2017
Background/Aims: Hemodialysis patients have poor prognosis due to increased prevalence of cardiovascular diseases. Treatment to suppress increases in sympathetic nerve activity and QT prolongation may have the potential to reduce the occurrence of these ...
Takeshi Iida, Satoshi Morimoto, Yoshifumi Amari, Takashi Ando, Atsuhiro Ichihara   +4 more
doaj   +1 more source

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay, Lynn C. Lunsonga, Peter E. Light, Khaled Barakat   +3 more
wiley   +1 more source

Absence of relevant QT interval prolongation in not critically ill COVID-19 patients

Scientific Reports, 2020
SARS-CoV-2 is a rapidly evolving pandemic causing great morbimortality. Medical therapy with hydroxicloroquine, azitromycin and protease inhibitors is being empirically used, with reported data of QTc interval prolongation.
Juan Jiménez-Jáimez, Rosa Macías-Ruiz, Francisco Bermúdez-Jiménez, Ricardo Rubini-Costa, Jessica Ramírez-Taboada, Paula Isabel García Flores, Laura Gallo-Padilla, Juan Diego Mediavilla García, Concepción Morales García, Sara Moreno Suárez, Celia Fignani Molina, Miguel Álvarez López, Luis Tercedor   +12 more
doaj   +1 more source

Metal‐Free Ternary‐Composite Aerogel Based on Graphitic Carbon Nitride, Graphene Oxide, and β‐Cyclodextrin for Synergistic Adsorption and Photodegradation of Organic Dyes

Small, EarlyView.
A novel metal‐free g‐C3N4/GO/β‐CD aerogel exhibits a high adsorption capacity of 653.2 mg/g for RhB. The synergistic adsorption‐degradation effect of the aerogel enables the complete elimination of organic dyes. Fixed‐bed and recyclability tests demonstrate its potential for continuous industrial wastewater treatment.
Yuan Yu, Ke Zhou, Lu Shang, Yuting Zou, Qing Yin, Shengzhe Wang, Na Chang, Yuting Wen, Jun Li   +8 more
wiley   +1 more source

Additive Manufacturing of Hot‐Work Tool Steel by In Situ Alloying Using Laser Powder Bed Fusion and Directed Energy Deposition—Strategies to Improve Chemical Homogeneity

steel research international, EarlyView.
To support future alloy development a powder mixture is processed by laser additive manufacturing. The powder mixture containing Mo‐ and W‐rich tracers is processed by powder bed fusion using single and double laser exposure and by directed energy deposition which provides drastically enlarged melt pools.
Felix Großwendt, Sebastian Weber, Jonathan Lentz   +2 more
wiley   +1 more source

Propranolol can correct prolonged QT intervals in patients with cirrhosis

Frontiers in Pharmacology
Background:Prolonged QT intervals are extremely common in patients with cirrhosis and affect their treatment outcomes. Propranolol is often used to prevent gastroesophageal variceal hemorrhage in patients with cirrhosis; however, it is uncertain whether ...
Huanqin Han, Junlian Chen, Zhirong Deng, Tingting Li, Xiaoying Qi, Wei Deng, Zunge Wu, Chuli Xiao, Weiqiang Zheng, Yujun Du   +9 more
doaj   +1 more source

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source

The Effects of the Adenosine Receptor Antagonists on the Reverse of Cardiovascular Toxic Effects Induced by Citalopram In-Vivo Rat Model of Poisoning

Balkan Medical Journal, 2015
Background: Citalopram is a selective serotonin reuptake inhibitor that requires routine cardiac monitoring to prevent a toxic dose. Prolongation of the QT interval has been observed in acute citalopram poisoning.
Müjgan Büyükdeligöz, Nil Hocaoğlu, Kubilay Oransay, Yeşim Tunçok, Şule Kalkan   +4 more
doaj   +1 more source

Association of Cat Sensitization With Comorbid Asthma in Patients With Allergic Rhinitis: A Real‐World Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background The prevalence of allergic rhinitis (AR) and asthma (AS) comorbidity (AR + AS) is increasing and is associated with severe allergic symptoms. The impact of cat dander sensitization on AR + AS remains unclear. Methods In this retrospective study, 1154 patients with AR alone and 213 patients with AR + AS were enrolled at the Third ...
Wei‐Hao Wang, Xin Luo, Zhen‐Hao Xiao, Hong‐Kai Wang, Ya‐Na Zhang, Qin‐Tai Yang   +5 more
wiley   +1 more source

Real‐world comparative effects of slow‐release oral morphine vs. methadone on healthcare use for opioid use disorder: A population‐based target trial emulation

Addiction, EarlyView.
Abstract Aims To examine the comparative effects of slow‐release oral morphine (SROM) vs. methadone for the treatment of opioid use disorder (OUD) on healthcare use. Design This retrospective cohort study emulated a target trial using electronic medical record data from Vancouver Coastal Health Authority linked with population‐based administrative ...
Vivienne Y. Zhou, Nadia Fairbairn, Jingxin Lei, Rupinder Brar, Paxton Bach, M. Eugenia Socias   +5 more
wiley   +1 more source