Results 51 to 60 of about 1,019,184 (189)

Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine

Case Reports in Cardiology, 2016
We present a case of a syncopal episode resulting from significant QT interval prolongation in a patient on hydroxychloroquine for the treatment of systemic lupus erythematosus and end stage renal disease.
John P. O’Laughlin, Parag H. Mehta, Brian C. Wong   +2 more
doaj   +1 more source

QT is longer in drug-free patients with schizophrenia compared with age-matched healthy subjects. [PDF]

PLoS ONE, 2014
The potassium voltage-gated channel KCNH2 is a well-known gene in which mutations induce familial QT interval prolongation. KCNH2 is suggested to be a risk gene for schizophrenia.
Kumiko Fujii, Yuji Ozeki, Hiroaki Okayasu, Yumiko Takano, Takahiro Shinozaki, Hiroaki Hori, Masami Orui, Minoru Horie, Hiroshi Kunugi, Kazutaka Shimoda   +9 more
doaj   +1 more source

The risk of treatment-induced QT interval prolongation

, 2022
Objective: QT interval prolongation can increase patients' hospital tay and mortality rate. This study aims to determine the incidence of drug-induced QT interval prolongation and establish which QT Interval measurement method is the most appropriate for
Zavaleta-Monestel,Esteban, Chaverri-Fernández,José Miguel, Fallas-Mora,Abigail, Escalona-Rodríguez,Rocío, Díaz-Madriz,Jose\u301 Pablo, Cordero-García,Eugenia   +5 more
core   +1 more source

Prolonged QT Interval in a Patient With Coronavirus Disease-2019: Beyond Hydroxychloroquine and Azithromycin

Journal of Investigative Medicine High Impact Case Reports, 2020
Recent reports have suggested an increased risk of QT prolongation and subsequent life-threatening ventricular arrhythmias, particularly torsade de pointes, in patients with coronavirus disease-2019 (COVID-19) treated with hydroxychloroquine and ...
B K Anupama MBBS, Soumya Adhikari MBBS, Debanik Chaudhuri MD   +2 more
doaj   +1 more source

Congenital Short QT Syndrome [PDF]

, 2004
Long QT intervals in the ECG have long been associated with sudden cardiac death. The congenital long QT syndrome was first described in individuals with structurally normal hearts in 1957.1 Little was known about the significance of a short QT interval.
Antzelevitch, Charles, Johnson Francis, Francis, Johnson, Charles Antzelevitch   +3 more
core  

Thyroid hormones regulate cardiac repolarization and QT-interval related gene expression in hiPSC cardiomyocytes

Scientific Reports, 2022
Prolongation of cardiac repolarization (QT interval) represents a dangerous and potentially life-threatening electrical event affecting the heart. Thyroid hormones (THs) are critical for cardiac development and heart function.
Alessandra Ulivieri, Luca Lavra, Fiorenza Magi, Alessandra Morgante, Leonardo Calò, Patrizio Polisca, Leila B. Salehi, Salvatore Sciacchitano   +7 more
doaj   +1 more source

Comparison of Corrected QT Interval Prolongation in Young and Middle-aged Adults after First-time ST-Elevation Myocardial Infarction at Cardiac Care Facility: A Cross-Sectional Study

Life and Science
Objective: To compare corrected QT interval prolongation in young and middle-aged adults after first-time ST-elevation myocardial infarction and to determine its association with selected clinical variables. Study Design: Analytical cross-sectional study.
Arif Khaliq, Mohsin Saif, Sidra Saif, Waheed Ur Rehman, Riaz Haider, Tahir Zaman   +5 more
doaj   +1 more source

Life-Threatening QT Prolongation in a Preterm Infant

American Journal of Perinatology Reports, 2014
Introduction Temporary QT-interval prolongation following intracranial hemorrhage and hydrocephalus has been repeatedly reported in adults. Case We report a case of excessive QT prolongation with sudden bradycardia resulting in 2:1 ...
Christian Paech, Roman Gebauer, Matthias Knüpfer   +2 more
doaj   +1 more source

Methods of Assessment and Clinical Relevance of QT Dynamics [PDF]

, 2005
The dependence on heart rate of the QT interval has been investigated for many years and several mathematical formulae have been proposed to describe the QT interval/heart rate (or QT interval/RR interval) relationship. While the most popular is Bazett’s
Agata, Musialik-Lydka, Beata, Sredniawa, Piotr, Jarski, Anna, Sliwinska, Zbigniew, Kalarus   +4 more
core  

Quality of drug label information on QT interval prolongation [PDF]

, 2014
Background: Information regarding QT-prolongation in the drug label may vary between products. This could lead to suboptimal risk minimization strategies.
Rutten, Frans H., Mol, Peter G.M., Mol, Peter G.M.; id_orcid, De Boer, Anthonius, Hoes, Arno W., De Bruin, Marie L., Warnier, Miriam J., Holtkamp, Frank A.   +7 more
core   +2 more sources