Results 211 to 220 of about 55,181 (324)

Frequency of QT Interval Prolongation in ChronicLiver Disease Patients

, 2019
Wali Khan Mashwani, Tahir Ullah Khan
openalex   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Incidence and Risk Factors of QT Prolongation and Torsades de Pointes following Intravenous Amiodarone Administration for Atrial Fibrillation: A Cohort Study. [PDF]

Arch Acad Emerg Med
Wongsalap Y, Miliam W, Deesham S, Thepsaen A, Churasae A, Poolpun D, Thongsri T, Saksit N.   +7 more
europepmc   +1 more source

QT prolongation in the STREAM Stage 1 Trial. [PDF]

Int J Tuberc Lung Dis, 2022
Hughes G, Bern H, Chiang CY, Goodall RL, Nunn AJ, Rusen ID, Meredith SK.   +6 more
europepmc   +1 more source

QT PRODACT: Sensitivity and Specificity of the Canine Telemetry Assay for Detecting Drug-Induced QT Interval Prolongation

, 2005
Hiroyasu Miyazaki, Hiroyuki Watanabe, Tetsuya Kitayama, Masahiro Nishida, Yasuhiro Nishi, Koji Sekiya, Hideki Suganami, Keiji Yamamoto   +7 more
openalex   +2 more sources

Gap junctional and ephaptic coupling in cardiac electrical propagation: homocellular and heterocellular perspectives

The Journal of Physiology, EarlyView.
Abstract figure legend Intricate cellular electrical coupling networks in the heart. Various cell types couple the central cardiomyocyte through gap junctional contacts, with the exception of neurons. Whether ephaptic coupling (EpC) occurs in homocellular or heterocellular contexts beyond cardiomyocyte–cardiomyocyte interactions remains unclear ...
Xiaobo Wu, Laura Beth Payne, Robert G. Gourdie   +2 more
wiley   +1 more source

Overdose of Quetiapine-A Case Report with QT Prolongation. [PDF]

Toxics, 2021
Bertol E, Vaiano F, Argo A, Zerbo S, Trignano C, Protani S, Favretto D.   +6 more
europepmc   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

The Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo, Zachary D. Long, Arie O. Verkerk, Jose M. Ferrero, T. Alexander Quinn, Jose F. Rodriguez Matas   +5 more
wiley   +1 more source

Abnormal Ca²⁺ handling and reduced I_to contribute to citalopram-induced QT prolongation and cardiac arrhythmias. [PDF]

Front Pharmacol
Li Y, Xie J, Zheng Y, Li J, Zhao M, Liu L, Shen H, Lei M, Tan X, Xiao J, Liu X, Chen T.   +11 more
europepmc   +1 more source

Unraveling Structural Alerts in Marketed Drugs for Improving Adverse Outcome Pathway Framework of Drug-Induced QT Prolongation. [PDF]

Int J Mol Sci, 2023
Long W, Li S, He Y, Lin J, Li M, Wen Z.
europepmc   +1 more source