Pharmacogenomic markers associated with drug-induced QT prolongation: a systematic review. [PDF]
Bentestuen MS +9 more
europepmc +1 more source
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
Transgender-Affirming Hormone Therapies, QT Prolongation, and Cardiac Repolarization.
Grouthier V +8 more
europepmc +1 more source
Abnormal Ca<sup>2+</sup> handling and reduced I<sub>to</sub> contribute to citalopram-induced QT prolongation and cardiac arrhythmias. [PDF]
Li Y +11 more
europepmc +1 more source
Association between QT prolongation and cardiovascular mortality in cancer patients. [PDF]
Chan CH +5 more
europepmc +1 more source
hERG1 channels and potential therapeutics for long QT syndrome
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider +3 more
wiley +1 more source
The Frequency and Incidence of QT Prolongation With Extended Use of Bedaquiline or Delamanid in a Large, Multi-Country Multidrug-Resistant/Rifampicin-Resistant Tuberculosis Cohort. [PDF]
Khan U +32 more
europepmc +1 more source
Context‐free graphs and their transition groups
Abstract Starting from context‐free inverse graphs, we introduce a new class of groups and study their structural properties. We establish closure properties, show that their coword problems are context‐free, analyze torsion elements, and realize them as subgroups of the asynchronous rational group.
Daniele D'Angeli +3 more
wiley +1 more source
Therapeutic Drug-Drug Interactions (DDIs) Causing QT Prolongation in Patients With Cancer: A Systematic Review and Meta-Analysis. [PDF]
Ramasubbu SK +4 more
europepmc +1 more source

