Results 211 to 220 of about 30,871 (260)

Statistical Characterization of QT Prolongation

Journal of Biopharmaceutical Statistics, 2010
The appropriate assessment of QT prolongation remains controversial. We suggest that before the relative merits of various methods can be evaluated, we must state what we assume an assessment of QT prolongation should be about. As a general framework for the assessment of QT prolongation we propose that an assessment of "absolute" or "uncorrected" QT ...
Robert, Schall, Arne, Ring
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Antipsychotics and QT prolongation

Acta Psychiatrica Scandinavica, 2003
Objective:  To evaluate literature relating to cardiac QT prolongation and the use of antipsychotic drugs.Method:  Literature searches of EMBASE, Medline, PsychLIT were performed in December 2001 and reference sections of retrieved papers scrutinized for further relevant reports.Results:  The Cardiac QTc interval is difficult to measure precisely or ...
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Syncope With Prolonged QT Interval

Archives of Pediatrics & Adolescent Medicine, 1976
Four children with syncope had a prolonged QT interval on the electrocardiogram. Neurologic studies were negative. One patient had associated deaf mutism, one had a family history of sudden death and prolonged QT interval, and two had ventricular arrhythmias while being monitored in the hospital.
J P, Frank, D Z, Friedberg
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Acquired QT Prolongation

Cardiology in Review, 1998
QT interval prolongation can be caused by several drugs. Torsade de pointes (TdP) is a form of ventricular proarrhythmia associated with QT interval prolongation, and in some cases, the development of U waves. The mechanism of TdP is believed to be related to an abnormality of repolarization in the ventricular myocardium and the development of early ...
, Fu, , Clemo, , Ellenbogen
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Antipsychotic drugs and QT prolongation

International Clinical Psychopharmacology, 2005
Antipsychotic drugs (AD) are effective and frequently prescribed to more females than males. AD may cause serious cardiovascular side-effects, including prolonged QT interval, eventually leading to torsades de pointes (TdP) and sudden death. Epidemiologic data and case-control studies indicate an increased rate of sudden death in psychiatric patients ...
Claudia, Stöllberger, Johannes O, Huber, Josef, Finsterer   +2 more
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Gatifloxacin and Prolonged QT Interval

The American Journal of the Medical Sciences, 2004
We report the case of a 54-year-old woman who, while being treated for acute sinusitis with gatifloxacin, presented with syncope and was found to have a markedly prolonged QT interval. After stopping gatifloxacin, the QT interval normalized. We speculate that her episode of syncope was caused by a ventricular arrhythmia that resulted from an increased ...
Shoaib R, Ansari, Nagesh, Chopra
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QT prolongation and arrhythmia suppression

American Heart Journal, 1985
It seems possible to draw some overall conclusions from the data on antiarrhythmic drug-induced QT prolongation and its role in drug effects. At one end of the spectrum are patients with highly exaggerated QT responses during therapy, most often in the setting of hypokalemia and long cycle lengths (post-ectopic pauses, bradycardia).
D M, Roden, R L, Woosley
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Prolonged corrected QT dispersion

Oncology Reports, 1997
The anthracyclines are antibiotics effective in the treatment of many malignancies. However, their usefulness is limited by the development of potentially acute or chronic cardiotoxicity. No definitive guidelines exist for monitoring cardiac function during and after anthracyclines although methods have been suggested.
M, Orditura, B, Sarubbi, F, Devita, V, Ducceschi, L, Santangelo, A, Cariello, A, Iacono, G, Catalano   +7 more
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Arrhythmogenic mechanisms of QT prolonging drugs: Is QT prolongation really the problem?

Journal of Electrocardiology, 2004
Torsade de Pointes (TdP) is an atypical ventricular arrhythmias associated with the acquired and congenital forms of the long QT syndrome. The substrate for the arrhythmia develops as a consequence of the amplification of electrical heterogeneities intrinsic to the ventricular myocardium.
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Prolonged QT-Interval Syndromes

JAMA: The Journal of the American Medical Association, 1986
PROLONGATION of the QT interval, either on a congenital or an acquired basis, is associated with an increased likelihood of malignant ventricular arrhythmias. 1-3 Patients with QT prolongation frequently develop recurrent attacks of syncope or may present with sudden death.
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