Results 61 to 70 of about 30,871 (260)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun   +4 more
wiley   +1 more source

Arsenic trioxide-induced QT interval prolongation: A case report

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2017
QT prolongation refers to the prolonged QT interval in electrocardiography (ECG) which can even lead to life-threatening events such as ventricular arrhythmias, torsades de pointes, etc., several drugs can cause QT prolongation which includes sotalol ...
Devika Mohan   +2 more
doaj   +1 more source

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor   +11 more
wiley   +1 more source

Drug-induced QT interval prolongation in cancer patients

open access: yesOncology Reviews, 2011
Cancer patients are at an increased risk for QT interval prolongation and subsequent potentially fatal Torsade de pointes tachycardia due to the multiple drugs used for treatment of malignancies and the associated symptoms and complications.
Torben K. Becker, Sai-Ching J. Yeung
doaj   +1 more source

Deciphering Polarity Effects of Polymer to Regulate Li+ Ionic Environment in Solid Polymer Electrolytes for Solid‐State Lithium Batteries

open access: yesCarbon Energy, EarlyView.
We elucidate the fundamental influences of polymer polarity on Li+ ionic environments in solid polymer electrolytes by considering four critical components: Li+, FSI−, residual solvents, and polymer matrix. Beyond facilitating LiFSI dissociation and Li+ transport, our findings underscore previously overlooked roles of polymer polarity, thereby ...
Ji‐Oh Kim   +7 more
wiley   +1 more source

QT Prolongation [PDF]

open access: yesCanadian Pharmacists Journal / Revue des Pharmaciens du Canada, 2016
Kelly, Grindrod   +2 more
openaire   +2 more sources

QT Prolongation due to Graves’ Disease

open access: yesCase Reports in Cardiology, 2017
Hyperthyroidism is a highly prevalent disease affecting over 4 million people in the US. The disease is associated with many cardiac complications including atrial fibrillation and also less commonly with ventricular tachycardia and fibrillation. Many cardiac pathologies have been extensively studied; however, the relationship between hyperthyroidism ...
Zain Kulairi   +4 more
openaire   +3 more sources

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu   +15 more
wiley   +1 more source

Gas–Solid Interface‐Assisted Growth of Organic Semiconductor Single Crystals: Dimensions, Structures, Mechanisms, and Applications

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Gas–solid interface‐assisted growth strategies have unlocked precise control over crystal structure, morphology, dimension, and molecular packing. The obtained organic semiconductor single crystals represent the ideal candidates for high‐performance organic optoelectronic devices.
Tingyi Yan   +8 more
wiley   +1 more source

Association Between Disturbed Serum Phosphorus Levels and QT Interval Prolongation

open access: yesKidney International Reports
Introduction: QT interval prolongation is a risk factor for fatal arrhythmias and other cardiovascular complications. QT interval prolongation in patients on hemodialysis (HD) is not well understood.
Sho Sasaki   +6 more
doaj   +1 more source

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