Results 11 to 20 of about 35,025 (266)
Human QTL linkage mapping [PDF]
Genetica, 2008 Human quantitative trait locus (QTL) linkage mapping, although based on classical statistical genetic methods that have been around for many years, has been employed for genome-wide screening for only the last 10-15 years. In this time, there have been many success stories, ranging from QTLs that have been replicated in independent studies to those for
Laura, Almasy, John, Blangero
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G3: Genes, Genomes, Genetics, 2018 We illustrate, through two case studies, that “mean-variance QTL mapping”—QTL mapping that models effects on the mean and the variance simultaneously—can discover QTL that traditional interval mapping cannot.
Robert W. Corty +4 more
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Trends in Genetics, 1995 In the past 10 years, interest in applying the tools of molecular genetics to the problem of increasing world rice production has resulted in the generation of two highly saturated, molecular linkage maps of rice, and the localization of numerous genes and quantitative trait loci (QTLs).
S R, McCouch, R W, Doerge
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Advances in QTL Mapping in Pigs [PDF]
International Journal of Biological Sciences, 2007 Over the past 15 years advances in the porcine genetic linkage map and discovery of useful candidate genes have led to valuable gene and trait information being discovered. Early use of exotic breed crosses and now commercial breed crosses for quantitative trait loci (QTL) scans and candidate gene analyses have led to 110 publications which have ...
Rothschild, Max F +2 more
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Target Enrichment Improves Mapping of Complex Traits by Deep Sequencing
G3: Genes, Genomes, Genetics, 2016 Complex traits such as crop performance and human diseases are controlled by multiple genetic loci, many of which have small effects and often go undetected by traditional quantitative trait locus (QTL) mapping.
Jianjun Guo +3 more
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QTL Mapping to QTL Cloning: Mice to the Rescue [PDF]
Genome Research, 1997 With the availability of dense, highly informative marker maps, it has recently become feasible to map genes (Quantitative Trait Loci or QTL) accounting for part of the heritability of continuously distributed traits in experimental crosses as well as outbred populations. QTL mapping efforts have almost invariably revealed a limited number of loci with
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A robust QTL mapping procedure [PDF]
Journal of Statistical Planning and Inference, 2009 In quantitative-trait linkage studies using experimental crosses, the conventional normal location-shift model or other parameterizations may be unnecessarily restrictive. We generalize the mapping problem to a genuine nonparametric setup and provide a robust estimation procedure for the situation where the underlying phenotype distributions are ...
Zou, Fei +3 more
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Tools for quantitative trait locus mapping and genome-wide association study mapping: a review
浙江大学学报. 农业与生命科学版, 2014 One of the key objectives in genomics studies is to understand genetic architecture of complex traits and diseases. Quantitative trait locus (QTL) mapping and genome-wide association study (GWAS) mapping have been using to dissect genetic architecture of
Md. Mamun Monir, Zhu Jun
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R/qtl: QTL mapping in experimental crosses
Bioinformatics, 2003 Abstract Summary: R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and
Karl W. Broman +3 more
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Identification of unconditional and conditional QTL for oil, protein and starch content in maize
Crop Journal, 2013 Oil, protein and starch are key chemical components of maize kernels. A population of 245 recombinant inbred lines (RILs) derived from a cross between a high-oil inbred line, By804, and a regular inbred line, B73, was used to dissect the genetic ...
Yuqiu Guo +6 more
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