Results 1 to 10 of about 3,776 (117)
The power of QTL mapping with RILs. [PDF]
PLoS ONE, 2012 QTL (quantitative trait loci) mapping is commonly used to identify genetic regions responsible to important phenotype variation. A common strategy of QTL mapping is to use recombinant inbred lines (RILs), which are usually established by several ...
Shohei Takuno +2 more
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postQTL: a QTL mapping R workflow to improve the accuracy of true positive loci identification
BMC Research Notes, 2022 Objective The determination of the location of quantitative trait loci (QTL) (i.e., QTL mapping) is essential for identifying new genes. Various statistical methods are being incorporated into different QTL mapping functions.
Prashant Bhandari, Tong Geon Lee
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Behavior Genetics, 2004 The standard variance components method for mapping quantitative trait loci is derived on the assumption of normality. Unsurprisingly, statistical tests based on this method do not perform so well if this assumption is not satisfied. We use the statistical concept of copulas to relax the assumption of normality and derive a test that can perform well ...
Basrak, B. +4 more
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Joint QTL linkage mapping for multiple-cross mating design sharing one common parent. [PDF]
PLoS ONE, 2011 BackgroundNested association mapping (NAM) is a novel genetic mating design that combines the advantages of linkage analysis and association mapping. This design provides opportunities to study the inheritance of complex traits, but also requires more ...
Huihui Li +4 more
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Inclusive Composite Interval Mapping of QTL by Environment Interactions in Biparental Populations. [PDF]
PLoS ONE, 2015 Identification of environment-specific QTL and stable QTL having consistent genetic effects across a wide range of environments is of great importance in plant breeding. Inclusive Composite Interval Mapping (ICIM) has been proposed for additive, dominant
Shanshan Li, Jiankang Wang, Luyan Zhang
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R/qtl: high-throughput multiple QTL mapping [PDF]
Bioinformatics, 2010 AbstractMotivation: R/qtl is free and powerful software for mapping and exploring quantitative trait loci (QTL). R/qtl provides a fully comprehensive range of methods for a wide range of experimental cross types. We recently added multiple QTL mapping (MQM) to R/qtl.
Danny Arends +3 more
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Multi-QTL mapping for quantitative traits using epistatic distorted markers. [PDF]
PLoS ONE, 2013 The interaction between segregation distortion loci (SDL) has been often observed in all kinds of mapping populations. However, little has been known about the effect of epistatic SDL on quantitative trait locus (QTL) mapping.
Shang-Qian Xie, Jia Wen, Yuan-Ming Zhang
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Scientific Reports, 2023 In recent years multi-parental mapping populations (MPPs) have been widely adopted in many crops to detect quantitative trait loci (QTLs) as this method can compensate for the limitations of QTL analyses using bi-parental mapping populations.
Buddhika A. Dahanayaka, Anke Martin
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QTL Mapping Under Ascertainment [PDF]
Annals of Human Genetics, 2006 SummaryMapping quantitative trait loci (QTL) using ascertained sibships is discussed. It is shown that under the standard normality assumption of variance components analysis the efficient scores are unchanged by ascertainment, and two different schemes of ascertainment correction suggested in the literature are asymptotically equivalent.
J, Peng, D, Siegmund
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Estimating genetic variance contributed by a quantitative trait locus: A random model approach.
PLoS Computational Biology, 2022 Detecting quantitative trait loci (QTL) and estimating QTL variances (represented by the squared QTL effects) are two main goals of QTL mapping and genome-wide association studies (GWAS).
Shibo Wang, Fangjie Xie, Shizhong Xu
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