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QTL Mapping Using RIL Population
Genetic maps are an excellent tool for the analysis of important traits, the development of which is the result of the combined expression of several genes, enabling the genomic localization of the factors determining them. Such features, characterized by a normal distribution of values, are referred to as quantitative or polygenic.Paweł, Milczarski +2 more
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Meta-analysis of QTL Mapping Experiments
2012Meta-analysis is an important tool for integrating information from multiple quantitative trait loci (QTLs) studies. Pooling of results from several studies allows greater statistical power for QTL detection and more precise estimation of their genetic effects.
Xiao-Lin, Wu, Zhi-Liang, Hu
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Empirical Bayesian QTL Mapping
2012Empirical Bayesian is still a Bayesian method, but thehyperparameters (the parameters of the prior distribution) are not preselected by the investigators; instead, they are estimated from the same dataset as that used in the Bayesian analysis. Once the hyperparameters are estimated, they are used in the usual Bayesian analysis as if they were the true ...
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2012
So far we have learned the least-squares method, the weighted least squares method, and the maximum likelihood method for QTL mapping. These methods share a common problem in handlingmultiple QTL, that is, the problem ofmulticollinearity. Therefore, a model can include only a few QTL.
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So far we have learned the least-squares method, the weighted least squares method, and the maximum likelihood method for QTL mapping. These methods share a common problem in handlingmultiple QTL, that is, the problem ofmulticollinearity. Therefore, a model can include only a few QTL.
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Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature, 2022Vassily Trubetskoy +2 more
exaly
QTL Mapping in Plant Populations
2002The author derived explicit expressions for the maximum likelihood estimates of genetic parameters when the iterative EM algorithm is applied. These explicit formulas enable a comparison between new computed parameter estimates with ones that are calculated using the ECM algorithm, which is implemented in standard software (e. g.
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QTL Mapping in Outbred Pedigrees
1997This chapter reviews quantitative trait loci (QTL) mapping in outbred pedigrees: the influence of life history attributes, terminology and concepts unique to outbred QTL mapping, general pedigree designs, and the basics of QTL analyses. QTL mapping for outcrossed pedigrees is complicated by the absence of complete homozygosity in the parents.
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A systemic approach to mapping participation with low-carbon energy transitions
Nature Energy, 2021Jason Chilvers +2 more
exaly