Results 11 to 20 of about 7,447 (129)

Reaction of benzoxasilocines with aromatic aldehydes: Synthesis of homopterocarpans

open access: yesBeilstein Journal of Organic Chemistry, 2007
Condensation of 2H-benzo[g][1,2]oxasilocines with aromatic aldehydes in the presence of boron trifluoride affords mixtures of cis/trans 2-phenyl-3-vinylchromans with moderate yields.
Míriam Álvarez-Corral   +5 more
doaj   +1 more source

Synthesis of Pterocarpans

open access: yesNatural Product Communications, 2011
The total synthesis of natural pterocarpans and analogs is reviewed.
Leticia Jiménez-González   +4 more
doaj   +1 more source

Binding-driven reactivity attenuation enables NMR identification of selective drug candidates for nucleic acid targets

open access: yesCommunications Chemistry, 2022
NMR spectroscopy could be a robust and reliable method for binding detection in drug discovery, but DNA/RNA targets remain challenging to analyze. Here, the authors explore the perturbation of the ligand reactivity caused by complex formation as a ...
Laura Díaz-Casado   +7 more
doaj   +1 more source

Synthetic scope and DFT analysis of the chiral binap–gold(I) complex-catalyzed 1,3-dipolar cycloaddition of azlactones with alkenes

open access: yesBeilstein Journal of Organic Chemistry, 2013
The 1,3-dipolar cycloaddition between glycine-derived azlactones with maleimides is efficiently catalyzed by the dimeric chiral complex [(Sa)-Binap·AuTFA]2.
María Martín-Rodríguez   +6 more
doaj   +1 more source

A Convenient Synthesis of the Central Core of Helioporins, -Pseudopterosins and Pseudopterosins BCA-Annulation Sequence

open access: yesNatural Product Communications, 2008
A convenient synthesis of the central core of helioporins, seco -pseudopterosins and pseudopterosins in racemic form is reported, using a Suzuki coupling (A-ring formation)-Friedel-Crafts acylation sequence, followed by synthetic elaboration of the ...
Gema Esteban   +3 more
doaj   +1 more source

Removing lead from water with carboxylate dendrimers and magnetic nanoparticles modified with carboxylate dendrimers

open access: yesApplied Water Science, 2023
Contamination of water with heavy metals as lead (Pb2+) is a relevant problematic issue. In this work, we have tested different types of dendritic materials for lead removal from water and further recovery. The systems employed are magnetic nanoparticles
David Rincón-Montón   +5 more
doaj   +1 more source

Chiral gold(I) vs chiral silver complexes as catalysts for the enantioselective synthesis of the second generation GSK-hepatitis C virus inhibitor

open access: yesBeilstein Journal of Organic Chemistry, 2011
The synthesis of a GSK 2nd generation inhibitor of the hepatitis C virus, by enantioselective 1,3-dipolar cycloaddition between a leucine derived iminoester and tert-butyl acrylate, was studied.
María Martín-Rodríguez   +4 more
doaj   +1 more source

Nanoscale Biocompatible Structures Generated from Fluorinated Tripodal Phenylenes on Gold Nanoprisms

open access: yesChemistryOpen, 2022
Modification of gold substrates with a stable, uniform and ultrathin layer of biocompatible materials is of tremendous interest for the development of bio‐devices.
Prof. Dr. Miguel García‐Castro   +5 more
doaj   +1 more source

Tandem cross enyne metathesis (CEYM)–intramolecular Diels–Alder reaction (IMDAR). An easy entry to linear bicyclic scaffolds

open access: yesBeilstein Journal of Organic Chemistry, 2015
A new tandem cross enyne metathesis (CEYM)–intramolecular Diels–Alder reaction (IMDAR) has been carried out. It involves conjugated ketones, esters or amides bearing a remote olefin and aromatic alkynes as the starting materials.
Javier Miró   +5 more
doaj   +1 more source

Uso de modelado molecular como herramienta didáctica en el primer curso de grado de Química Orgánica

open access: yesEducación Química, 2018
El primer curso de Química Orgánica (Química Orgánica 101) de la Facultad de Química, Universidad de la República (Montevideo, Uruguay) se dicta para las carreras de Química Farmacéutica, Ingeniería Química, Química, Bioquímica Clínica e Ingeniería en ...
Gustavo Seoane   +9 more
doaj   +1 more source

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