Results 31 to 40 of about 7,447 (129)
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.Oxidized graphene rich in carboxylic acid groups obtained via a simple electrochemical exfoliation route is shown to tackle the main challenges of aqueous Zn‐ion batteries (AZIBs), specifically short Zn anode cycle life and sluggish cathode reaction kinetics.
Enrique Álvarez‐Rubiera +9 more
wiley +1 more source
Green Chemistry Letters and Reviews, 2022 Mechanochemistry is a powerful tool to develop environmentally benign syntheses of active pharmaceutical ingredients. In this context, we report here the synthesis of the anti-epileptic agent rufinamide through a one-pot sequential multi-component ...
Jorge Gómez-Carpintero +4 more
doaj +1 more source
Click Bioconjugation of Aza‐BODIPY Fluorophores to LfcinB Peptides for Improved Biocompatibility
European Journal of Organic Chemistry, EarlyView.Click bioconjugation attaches NIR aza‐BODIPY fluorophores to LfcinB‐derived anticancer peptides via CuAAC and thiol‐maleimide chemistry. Conjugates exhibit improved predicted solubility while retaining strong NIR absorption (703–730 nm). Peptide‐aza‐BODIPY conjugates induce apoptotic morphology in HeLa cancer cells.
A. Verónica Rodríguez‐Mayor +6 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster +13 more
wiley +2 more sources
European Journal of Organic Chemistry, EarlyView.A comprehensive DFT conformational study of Grignard additions to α‐alkoxy nitrones reveals that the reaction proceeds through a dinuclear α‐chelated transition structure in which the nitrone oxygen coordinates two magnesium centers. Other common additives, such as zinc dichloride, boron trifluoride, and dimethylaluminum chloride, were also studied ...
Manuel Pedrón +2 more
wiley +1 more source
SÍNTESIS DE DERIVADOS DE XANTENO EN UN LÍQUIDO IÓNICO
Avances en Ciencias e Ingeniería, 2019 This paper describes a simple and efficient procedure for obtaining an ionic liquid, 1,3-dimethylimidazolium methylsulfate, and its application in the synthesis of various xanthene derivatives, by coupling reactions of benzaldehyde or substituted ...
María E. Choque-Zárate +3 more
doaj
Communications ChemistryThe functionalization of challenging unactivated C(sp 3)–H bonds was achieved electrocatalytically via hydrogen atom transfer and without mediators. This was possible through the sole activation of the surface of the Glassy Carbon Electrode (GCE) in an ...
Loris Laze +2 more
doaj +1 more source
Delivery of Therapeutic Biopolymers Employing Silica-Based Nanosystems
Pharmaceutics, 2023 The use of nanoparticles is crucial for the development of a new generation of nanodevices for clinical applications. Silica-based nanoparticles can be tailored with a wide range of functional biopolymers with unique physicochemical properties thus ...
Zoila Gándara +2 more
doaj +1 more source
European Journal of Organic Chemistry, EarlyView.An efficient gold‐catalyzed intramolecular cyclization of indole‐tethered alkynes using AgNTf2 as an additive has been developed, which provides bioactive exocyclic alkenyl tetrahydrocarbazoles with up to 85% yield. Control experiments and DFT studies indicate that the reaction proceeds via a 6‐exo‐dig cyclization pathway, with gold acetylide complexes
Haibo Mei +4 more
wiley +1 more source
Polymer Engineering &Science, EarlyView.Thermokinetic processing controls graphene fragmentation and dispersion in HDPE, promoting heterogeneous nucleation and multistep crystallization. The balance between nucleation enhancement and chain mobility restriction governs the final crystalline structure and material performance.
Lucas J. S. Nascimento +4 more
wiley +1 more source