Results 151 to 160 of about 917,193 (286)

Ganoderic Acids Alleviate Dexamethasone‐Induced Muscle Atrophy Potentially via Regulating Protein Synthesis/Degradation, Attenuating Oxidative Stress, and Antagonizing Glucocorticoid Receptor

open access: yesPhytotherapy Research, EarlyView.
This work proposes a mechanism in which ganoderic acid A (GAA), the active monomer of ganoderic acids (GA) from Ganoderma lucidum, binds to the glucocorticoid receptor (GR) to form a GR‐GAA complex, thereby inhibiting DEX‐induced GR activation. This inhibition suppresses oxidative stress (ROS, MDA and 4‐HNE) by upregulating antioxidant proteins (Nrf2 ...
Kecheng Tang   +10 more
wiley   +1 more source

Training on the quadriceps of individuals with rheumatoid arthritis: A systematic review and meta‐analysis

open access: yesRheumatology &Autoimmunity, EarlyView.
Physical training significantly improves quadriceps strength in patients with rheumatoid arthritis. No serious adverse events were reported. Abstract Background Rheumatoid arthritis is a chronic, systemic disease in which patients can benefit from physical exercise.
Mariana Laís Boaretto   +6 more
wiley   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

open access: yesSmart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang   +8 more
wiley   +1 more source

Quadriceps muscle status after medial-pivot versus ultracongruent total knee arthroplasty using localized bioimpedance analysis: a randomized exploratory study. [PDF]

open access: yesArthroplasty
Pedemonte-Parramón G   +5 more
europepmc   +1 more source

Strengthening Techniques of the Quadriceps Muscles: An Electromyographic Evaluation [PDF]

open access: yesPhysical Therapy, 1966
R O, Allington   +3 more
openaire   +2 more sources

Anatomical–Motor Level Discrepancy in Prenatal Diagnosis of Open Spinal Dysraphism: A 12‐Year Retrospective Observational Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objectives To quantify the discrepancy between anatomical and motor levels in foetuses with open spinal dysraphism and identify prenatal factors associated with this difference. We also examined associations between anatomical level and ultrasound findings. Design Retrospective observational study.
Silvia Arévalo   +8 more
wiley   +1 more source

Indirect fractures in long bones resulting from gunshot trauma: Occurrence, characterization, and need for additional research

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Indirect fractures from gunshot wounds can occur when a projectile impacts soft tissue without making direct contact with the bone. Existing biomechanical and clinical research suggests that indirect fractures result in lower levels of comminution, and that resultant fracture patterns can resemble those seen in blunt force trauma (e.g., wedge ...
Alexandra Semma Tamayo   +4 more
wiley   +1 more source

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