Results 51 to 60 of about 129,208 (280)
Iterative Selection of DNA Nanostructures for Cellular Uptake
Advanced Materials, EarlyView.DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar +4 more
wiley +1 more source
Regional sustainable development using a Quadruple Helix approach in Japan
Regional Studies, Regional Science, 2023 This study analyses the knowledge-sharing process and its outcomes among stakeholders (i.e., academia, industry, government and civil society) in the context of a regional sustainability-oriented project held in Ena City, central Japan, by using the ...
Muhammad Mohsin Hakeem +3 more
doaj +1 more source
Fiber‐Format Flexible Linear Electrostatic Motors
Advanced Materials, EarlyView.A flexible coaxial fibre‐format electrostatic motor enables backdrivable and reversible linear actuation with high force density and functionality under bending, offering a scalable actuation platform for soft and wearable robotics. ABSTRACT Linear motion is fundamental to robotics, yet existing solutions are either rigid electromagnetic motors or ...
Sylvain Schaller, Herbert Shea
wiley +1 more source
Media and culture-based public in the quadruple helix innovation model
BizInfoSpiral innovation models challenge the technological and economic determinism inherent in linear "science and technology push" and "demand pull" frameworks that explain the primary drivers of innovation.
Slobodan Cvetanović +2 more
doaj +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Quadruple Helix Stakeholders and Social Innovation in the Energy Transition
Symphonya, 2023 Social innovation (SI) aims at improving people’s life when technological or business innovations are not sufficient. However, the classic Triple Helix (TH) theory does not explicitly deal with SI, and relegates civil society to a passive role.
Michele Coletti +2 more
doaj +1 more source
Advanced Science, EarlyView.Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su +13 more
wiley +1 more source
A hypothetical improvement of the quadruple helix model of innovation
Acta Commercii, 2022 Orientation: Innovation is forged by sub-revolutions as described by the quadruple helix (QH) model. Research purpose: Innovation model formation is complex, and the useful QH model can develop and improve to be exemplary. Motivation for the study: The rationale of the study is to validate and improve the QH model with additional concepts, fresh ...
Van Schalkwyk, Riaan Dirkse +1 more
openaire +3 more sources
Polarization Dynamics in Ferroelectrics: Insights Enabled by Machine Learning Molecular Dynamics
Advanced Science, EarlyView.Machine learning molecular dynamics is presented as a route to capture polarization switching, domain wall kinetics, topological polar textures, and polar mechanical coupling beyond the limits of conventional atomistic methods. This Perspective surveys recent progress and identifies key methodological directions, including long‐range electrostatics ...
Dongyu Bai +3 more
wiley +1 more source
Advanced Science, EarlyView.Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang +9 more
wiley +1 more source