Results 1 to 10 of about 50,578 (264)

Cis-trans isomerization of peptoid residues in the collagen triple-helix [PDF]

open access: yesNature Communications, 2023
Cis-peptide bonds are rare in proteins, and building blocks less favorable to the trans-conformer have been considered destabilizing. Although proline tolerates the cis-conformer modestly among all amino acids, for collagen, the most prevalent proline ...
Rongmao Qiu   +7 more
doaj   +2 more sources

Eight Triplex-Binding Molecules from Four Chemical Classes Broadly Recognize the MALAT1 Triple Helix [PDF]

open access: yesMolecules
RNA triple helices are relatively understudied, including their interactions with small molecules. In this study, we evaluated eight previously reported triplex-binding molecules (TBMs) for their functional effects on the premature and mature MALAT1 ...
Madeline M. Mousseau   +3 more
doaj   +2 more sources

The impossibility of the triple helix

open access: yesPrometheus, 2020
A dynamic model that distinguishes between slow and fast processes shows that a triple helix model is impossible as a tool for promoting interdependencies among science, industry and government. We present a theorem to demonstrate
David Emanuel Andersson   +1 more
doaj   +2 more sources

The chromatin – triple helix connection

open access: yesBiological Chemistry, 2023
Abstract Mammalian genomes are extensively transcribed, producing a large number of coding and non-coding transcripts. A large fraction of the nuclear RNAs is physically associated with chromatin, functioning in gene activation and silencing, shaping higher-order genome organisation, such as involvement in long-range enhancer–promoter ...
Rodrigo Maldonado, Gernot Längst
openaire   +2 more sources

The transfer of corruptive routines from old industrial regions to innovation clusters: a blind spot in innovation studies

open access: yesTriple Helix, 2017
Resumen Como fracasan los programas de innovación y como se desvían de la vía legal las redes de innovación son problemas que carecen de una respuesta completa.
Christiane Gebhardt
doaj   +1 more source

'Innovation policy is a team sport' - insights from non-governmental intermediaries in Canadian innovation ecosystem

open access: yesTriple Helix, 2018
Resumen Tanto los responsables de la formulación de políticas públicas como los profesionales han adoptado el enfoque del ecosistema de innovación para administrar el flujo de información en la Triple Hélice. En este enfoque la relación de los actores de
Merli Tamtik
doaj   +1 more source

The Role the University Could Play in an Inclusive Regional Innovation System

open access: yesTriple Helix, 2018
Resumen Investigaciones recientes muestran que las universidades no suelen promover sistemas inclusivos de innovación. Este artículo examina el programa de innovación de la Universidad de Zhejiang que se dirige a áreas rurales de China y que busca ...
Wei Yao, Heng Li, Mosi Weng
doaj   +1 more source

Triple Helix Innovation Ecosystem: The Role of Small and Medium Enterprises Community in Enhancing Performance

open access: yesKvalita Inovácia Prosperita, 2023
Purpose: This study seeks to reveal the relationship between the triple helix innovation ecosystem and Small and Medium Enterprises (SMEs’) performance and the role of the SME community as the mediator between the triple helix innovation ecosystem and ...
Sunday Noya   +2 more
doaj   +1 more source

Triple Helix

open access: yesRevista dos Trabalhos de Iniciação Científica da UNICAMP, 2019
Triple helix is innovation process form which emerged with development from medieval until contemporary university model. Graduate thesis deals with various themes related to the changes that have drastically affected the functioning of the university as an institution, and led to the development of a Triple helix model, which emphasizes the importance
Mariana Zuliani Theodoro de Lima   +1 more
openaire   +4 more sources

Triple Helix and the evolution of ecosystems of innovation: the case of Silicon Valley

open access: yesTriple Helix, 2018
Resumen El ecosistema de innovación de Silicon Valley ha evolucionado en la última década. El objectivo de este estudio es el de entender cómo evoluciona ese ecosistema debido a cambios en el papel desempeñado por los agentes de la Triple Hélice, y en ...
Josep M. Pique   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy