Results 201 to 210 of about 182,803 (252)

Mössbauer spectroscopy in drug discovery: revealing Fe- and Fe-S cluster dependent targets. [PDF]

open access: yesExpert Opin Drug Discov
Chen J   +4 more
europepmc   +1 more source

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

open access: yesDrug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda   +9 more
wiley   +1 more source

First Occurrence of Fatal Intoxication Involving Methiodone (IC‐26) in Finland; a Medicolegal Autopsy Case Report

open access: yesDrug Testing and Analysis, EarlyView.
ABSTRACT Methiodone (IC‐26) is a non‐fentanyl novel synthetic opioid which has recently been detected in drug seizures in Europe. There is still limited data about the drug in published toxicological case work, both in non‐fatal and fatal cases. We present a medicolegal autopsy case report on a fatal intoxication in an individual undergoing opioid ...
Lasse Pakanen   +2 more
wiley   +1 more source

Chiroptics of In-Plane Excitons. [PDF]

open access: yesJ Phys Chem A
Sburlati S, Gustafson A, Kahr B.
europepmc   +1 more source

Estimating Illicit Stimulant Drug Consumption in Luxembourg Using Wastewater‐Based Epidemiology

open access: yesDrug Testing and Analysis, EarlyView.
Wastewater‐based epidemiology provided nationwide estimates of illicit stimulant consumption in Luxembourg, revealing higher urban use, weekend increases in cocaine and MDMA, and cocaine as the dominant stimulant. The approach offers an objective complement to conventional drug surveillance for informing public health and policy.
Nadine Berndt   +5 more
wiley   +1 more source

A Single‐Aliquot Strategy for Simultaneous Carbon Isotope Confirmation of 6‐Oxo‐Androstenedione and Testosterone Misuse in Doping Control

open access: yesDrug Testing and Analysis, EarlyView.
This method enables simultaneous carbon isotope confirmation of 6‐oxo‐androstenedione and testosterone markers from a single urine aliquot, using bench‐top extraction, two preparative HPLC steps with intermediate acetylation, and GC/C/IRMS analysis. It was fully validated according to WADA requirements, and real samples demonstrated its fitness for ...
Fábio Azamor de Oliveira   +7 more
wiley   +1 more source

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

open access: yesDevelopmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble   +2 more
wiley   +1 more source

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