Results 41 to 50 of about 908,678 (344)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

MOTIVATION FOR SPORTS AND TRAINING ACTIVITIES OF ATHLETES OF VARIOUS QUALIFICATIONS [PDF]

, 2021
Victoria Martynova, O.A. Kornev, A. V. Korneva   +2 more
openalex   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Transforming vocational education and training for nearly zero-energy building

Buildings & Cities, 2020
Nearly zero-energy building (NZEB) requires the training of millions of construction workers and significant upgrading of vocational education and training (VET) systems across the European Union.
Linda Clarke, Melahat Sahin-Dikmen, Christopher Winch   +2 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

ASPECTS OF EDUCATION IN THE EUROPEAN UNION IN THE ERA OF GLOBALIZATION [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2018
Sustainable development can be achieved by increasing the role played by education. At the same time, sustainable development contributes to improving the quality of life.
PETRICĂ SORIN ANGHELUȚĂ , CARMEN GEORGIANA BADEA   +1 more
doaj  

Predicting university performance in psychology: the role of previous performance and discipline-specific knowledge [PDF]

, 2008
Recent initiatives to enhance retention and widen participation ensure it is crucial to understand the factors that predict students' performance during their undergraduate degree.
Anthony Blurton, Browne M.W., Bryant F.B., Byrne B.M., Clarke C., Forbes D., Green S., James Hartley, Kline R.B., Liebermanh D.A., Lucy R. Betts, Mayer R.E., Miles J., Pratt M.W., Toal J., Tracey J. Elder, Zeegers P.   +16 more
core   +1 more source

КРИТЕРИИ ЭФФЕКТИВНОСТИ ФУНКЦИОНИРОВАНИЯ СИСТЕМЫ ДОПОЛНИТЕЛЬНОГО НЕПРЕРЫВНОГО ОБРАЗОВАНИЯ

Sovremennye Issledovaniâ Socialʹnyh Problem, 2015
В статье рассматриваются вопросы актуальные для сегодняшнего дня, так как система дополнительного профессионального образования кардинальным образом поменяла свои направления и приоритеты за последние несколько лет.
Yana Anatolievna Ilinskaya
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source