Results 41 to 50 of about 2,323,462 (303)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker +11 more
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Discover Civil EngineeringFragility curves as a powerful tool assess the possible damage to existing structures and estimate the probability of structural damage exceeding a given level of seismic damage for several levels of seismic ground motions.
Yaser Golestani, Elham Rajabi
doaj +1 more source
Frontiers in Public Health, 2022 BackgroundCognitive dysfunction is disproportionately prevalent among persons with opioid use disorder (OUD). Specific domains of cognitive dysfunction (attention, executive functioning, memory, and information processing) may significantly impede ...
Colleen B. Mistler +5 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
, 2017 Project Summary: The overarching research question that we address in our paper, “A Question of Respect: A Qualitative Text Analysis of the Canadian Parliamentary Committee Hearings on The Protection of Communities and Exploited Persons Act (PCEPA ...
Fuji Johnson, Genevieve
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Frontiers in Sociology, 2022 This paper draws on conceptual and analytical tools from cultural sociology to analyze media representations of the MMA right after the murder of a twenty-year-old boy, that took place in a small village in central Italy by a gang of young men, two of ...
Lorenzo Domaneschi, Oscar Ricci
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
RGO: Revista Gaúcha de Odontologia, 2019 Objective: The need to quantify pain and quality of life (QoL) is essential for professionals considering their therapeutic approach. The goal of this review is to identify the methods to perform qualitative and quantitative analysis of pain and QoL ...
Leandro Júnio MASULO +3 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Mathematical modelling for malaria under resistance and population movement
Revista Integración, 2020 In this work, two mathematical models for malaria under resistance are presented. More precisely, the first model shows the interaction between humans and mosquitoes inside a patch under infection of malaria when the human population is resistant to ...
Cristhian Montoya +1 more
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