Results 61 to 70 of about 5,539,207 (293)

Qualitative analysis of the dynamics of the time delayed Chua's circuit [PDF]

, 1997
IEEE TRANS. CIRCUITS SYST.
Biey, Mario, Bonani, Fabrizio, Gilli, Marco, Maio, I.   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Qualitative and Quantitative Analysis of (Na0.5bi0.5)tio3 Phase with the X-ray Diffraction Technique Using the Rietveld Method [PDF]

, 2011
The qualitative and quantitative phase analysis for (Na0.5Bi0.5)TiO3 (NBT) phase have been carried out by the X-ray diffraction technique using the Rietveld method. The NBT sample was synthesized by the solid reaction method.
Ahda, S. (Syahfandi), Sukirman, E. (Engkir)   +1 more
core  

Qualitative Analysis of POMDPs with Temporal Logic Specifications for Robotics Applications [PDF]

, 2015
We consider partially observable Markov decision processes (POMDPs), that are a standard framework for robotics applications to model uncertainties present in the real world, with temporal logic specifications. All temporal logic specifications in linear-
Chatterjee, Krishnendu, Chmelík, Martin, Gupta, Raghav, Kanodia, Ayush   +3 more
core   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Bianchi type I universe with viscous fluid: A qualitative analysis

, 2004
The nature of cosmological solutions for a homogeneous, anisotropic Universe given by a Bianchi type-I (BI) model in the presence of a Cosmological constant $\Lambda$ is investigated by taking into account dissipative process due to viscosity. The system
Banerjee, Barrow, Belinskii, Belinskii, Bijan Saha, Bronnikov, Bruni, Chimento, Desikan, Einstein, Einstein, Fay, Gavrilov, Guth, Hawking, Huang, Jacobs, Kamke, Krori, Langacker, Lidsey, Lidsey, Misner, Misner, Murphy, Pacher, Padmanabhan, Paul, Saha, Saha, Saha, Saha, Santos, Shinkai, Shinkai, Shinkai, V. Rikhvitsky, van Elst, Waga, Wald, Weinberg, Weinberg   +41 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

The Theoretical Nature of Systems Thinking. Perspectives on Systems Thinking in Biology Education

Frontiers in Education, 2018
Systems thinking has become synonymous to developing coherent understanding of complex biological processes and phenomena from the molecular level to the level of ecosystems.
Roald P. Verhoeff, Marie-Christine P. J. Knippels, Melde G. R. Gilissen, Kerst T. Boersma   +3 more
doaj   +1 more source