Results 31 to 40 of about 572,483 (253)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
An Exploration of the Viewpoints of Parents and Nurses on Care Provision in Neonatal Intensive Care Units [PDF]
Iranian Journal of Neonatology, 2015 Background: Infants are regarded as a vulnerable group in need of nursing care, particularly during NICU admission. Parents of these infants often experience emotional, psychological and physical upheavals.
Haydeh Heidari +2 more
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Challenges of respect as promoting healthy work environment in nursing: A qualitative study
Journal of Education and Health Promotion, 2019 CONTEXT: An increasingly common complaint of staff nurses in hospitals is not receiving respect. One of the strategies to create a healthy and positive work environment is to strengthen the respectful behaviors among nurses.
Azadeh Nouri +3 more
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Forum: Qualitative Social Research, 2000 The article describes an approach of systematic, rule guided qualitative text analysis, which tries to preserve some methodological strengths of quantitative content analysis and widen them to a concept of qualitative procedure.
Philipp Mayring
doaj
FOSTERING QUALITATIVE CONTENT ANALYSIS SKILLS THROUGH CASE METHOD
English Review: Journal of English Education, 2022 This study is aimed at demonstrating how students in the University of Bengkulu's master's program in Indonesian language education have improved their capacity to employ qualitative content analysis techniques.
Noermanzah Noermanzah +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
The Use of Qualitative Content Analysis in Case Study Research
Forum: Qualitative Social Research, 2006 This paper aims at exploring and discussing the possibilities of applying qualitative content analysis as a (text) interpretation method in case study research.
Florian Kohlbacher
doaj