Results 41 to 50 of about 28,755,285 (246)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Current mixed methods practices in qualitative research: A content analysis of leading journals

, 2015
Mixed methods research (MMR) has become increasingly popular in recent years. Yet, methodological challenges of mixing qualitative and quantitative data remain.
Hanson, William E, Radil, Amanda I, Zhang, Xiaozhou, Archibald, Mandy M   +3 more
core   +1 more source

Qualitative research and content analysis: A review of Graneheim and Lundman (2004 & 2020) [PDF]

حیات
Content analysis is a systematic and reproducible method through which large quantities of textual words are condensed into smaller, more understandable categories. This is achieved through coding principles.
Nahid Dehghan Nayeri, Fatemeh Bahramnezhad   +1 more
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Content analysis: What are they talking about? [PDF]

, 2006
Quantitative content analysis is increasingly used to surpass surface level analyses in Computer-Supported Collaborative Learning (e.g., counting messages), but critical reflection on accepted practice has generally not been reported.
Strijbos, JW, Martens, R.L., Jochems, Wim M. G., Jochems, Wim, Prins, F.J., Martens, RL, Strijbos, Jan Willem, Prins, FJ, Jochems, WMG Wim, Strijbos, Jan-Willem, Strijbos, J.W., Martens, Rob, Prins, Frans J., Prins, Frans, Jochems, W.M.G., Martens, Rob L.   +15 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Re-analysis as a Comparison of Constructions

Forum: Qualitative Social Research, 2000
An interesting methodological aspect of secondary analysis is that it enables comparisons between constructions that constitute qualitative data analysis.
Jochen Gläser, Grit Laudel
doaj  

Social multiplier effects: academics’ and practitioners’ perspective on the benefits of a tuberculosis operational research capacity-building program in Indonesia

Global Health Action, 2017
Background: The Tuberculosis Operational Research Group (TORG) implemented a capacity-building model involving academics and practitioners (i.e. clinicians or program staff) in an operational research (OR) team in Indonesia.
Ari Probandari, Yodi Mahendradhata, Bagoes Widjanarko, Bachti Alisjahbana, On behalf of Tuberculosis Operational Research Group (TORG)   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Interactive content analysis : evaluating interactive variants of non-negative Matrix Factorisation and Latent Dirichlet Allocation as qualitative content analysis aids [PDF]

, 2014
This thesis addressed issues that have prevented qualitative researchers from using thematic discovery algorithms. The central hypothesis evaluated whether allowing qualitative researchers to interact with thematic discovery algorithms and incorporate ...
Bakharia, Aneesha
core